The programmed cell death protein 1 (PD-1) is an inhibitory receptor on T cells and plays an important role in promoting cancer immune evasion. While ubiquitin E3 ligases for regulating PD-1 stability have been reported, deubiquitinase (DUB) governing PD-1 homeostasis to modulate tumor immunotherapy...
The proteome profiles of RNF223 knockdown and control pancreatic cancer cell lines were compared employing data independent acquisition(DIA) technology
Quantitative proteomic analysis of plasma from different time courses of fatal, severe, and mild COVID-19 patients was performed to assess the biological changes during treatment.