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ProteomicsMelatonin targets mitochondrial trifunctional enzyme HADHA to improve lipid metabolism in metabolic dysfunction-associated steatotic liver disease
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a clinicopathological syndrome characterized by abnormal accumulation of fat within hepatocytes, and there is currently no standardized clinical treatment available. Consequently, there is an urgent need to discover new pharmacologi...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD071550 | Pride
Melatonin Lipid metabolism Non-alcoholic steatotic liver disease 
ProteomicsCholesterol modulates the physiological response of nanoparticles by governing protein corona
Metabolome profile is an unexploited factor impacting the target efficacy and safety of nanomedicines by manipulating the formation of protein corona, and provide a novel way to develop personalized nanomedicines by harnessing disease-related metabolites.
ORGANISM(S): Homo Sapiens Mus Musculus Bos Taurus 
2023-03-24 | PXD041073 |
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