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MetabolomicsResearch on the quality markers of antioxidant activity of Kai-Xin-San based on spectrum-effect relationship
Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidan...
2023-12-21 | MTBLS8806 | MetaboLights
ProteomicsAXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
Axis inhibition protein 1 (AXIN), a scaffold protein interacting with various critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we identify AXIN acts as an effective regulator of antiviral in...
ORGANISM(S): Homo sapiens (Human) 
2024-10-31 | PXD055972 | Pride
Human Irf3 Axin1 
ProteomicsAXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
Axis inhibition protein 1 (AXIN), a scaffold protein interacting with various critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we identify AXIN acts as an effective regulator of antiviral in...
ORGANISM(S): Homo sapiens (Human) 
2024-11-01 | PXD055574 | Pride
Human Irf3 Axin1 
UnknownNanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes.
Not available
S-EPMC3947749 | biostudies-literature
UnknownThe hippo pathway effector YAP regulates motility, invasion, and castration-resistant growth of prostate cancer cells.
Not available
S-EPMC4372700 | biostudies-literature
UnknownHigh-throughput gene screen reveals modulators of nuclear shape.
Not available
S-EPMC7353136 | biostudies-literature
UnknownPancreatic Tumor Microenvironment Factor Promotes Cancer Stemness via SPP1-CD44 Axis.
Not available
S-EPMC10069715 | biostudies-literature
ProteomicsDifferential proteomics analysis on plasma from anlotinib-treated advanced non-small cell lung cancer patients
Anlotinib has been demonstrated to be effective in advanced non-small cell lung cancer (NSCLC) patients. DNA-seq- and RNA-seq-based anlotinib molecular mechanism and biomarker screening have been introduced in previous studies. The underlying value of proteomics for anlotinib study is still unclear....
ORGANISM(S): Homo Sapiens 
2020-03-05 | PXD017919 |
UnknownAsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines.
Not available
S-EPMC8222333 | biostudies-literature
ProteomicsProteomic Insights into Aprotinin’s Immunomodulatory Effects in Attenuating Renal Fibrosis in a Unilateral Ureteral Obstruction Model
Chronic kidney disease (CKD) is characterized by progressive renal fibrosis and immune dysregulation. Aprotinin, a broad-spectrum serine protease inhibitor, has shown dose-dependent effects on kidney function, but its role in chronic obstructive nephropathy remains unclear.
ORGANISM(S): Mus Musculus 
2025-05-03 | PXD063655 |
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