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We examined the biogenesis of mRNA-derived endogenous short-interfering RNAs (endo-siRNAs) in the disease vector mosquito, Aedes aegypti. Under standard conditions, mRNA-derived endo-siRNAs were produced from the bidirectional transcription of tail-tail overlapping gene pairs. Upon infection with th...
ORGANISM(S): Aedes aegypti 
Our previous study found that the expression of HSP17.4 is closely related to the occurrence of strawberry anthracnose. In this study, we used virus-mediated gene silencing technology and found that the HSP17.4 gene-silenced ‘Sweet Charlie’ plants were more susceptible to Colletotrichum gloeosporioi...
ORGANISM(S): Fragaria Vesca Subsp. Vesca 
2021-01-09 | PXD023494 |
Strawberry is an important economic crop in the world, and strawberry stigmata are vital to promote pollen germination and allow pollen tubes to enter into stigma tissue. Post-translational modification (PTM) of proteins can significantly affect protein structure and function, and plays a very impor...
ORGANISM(S): Fragaria Vesca 
2017-12-15 | PXD008475 |
Despite recent advances, rheumatoid arthritis (RA) patients remain refractory to therapy. Dysregulated overproduction of angiopoietin-like 4 protein (ANGPTL4) is thought to be contributed to the disease development. Therefore, interference with ANGPTL4 biological function may constitute a new therap...
ORGANISM(S): Rattus Norvegicus 
Histidyl dipeptides, such as carnosine, present in a micro-millimolar ranges in the heart, are synthesized via the enzyme carnosine synthase (Carns). These dipeptides facilitate glycolysis by proton buffering, form conjugates with reactive aldehydes, such as acrolein, and attenuate ischemia and repe...
ORGANISM(S): Mus <genus> 
2021-12-25 | PXD030647 |
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