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TranscriptomicsExpression profiling of the retinal pigment epithelium in zebrafish smarca4 mutant
Purpose: The purpose of this study was to develop a framework for analyzing RPE expression profiles from zebrafish eye mutants. Methods: The fish model we used was smarca4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4), a retinal dystrophic muta...
ORGANISM(S): Danio rerio 
2014-01-03 | E-GEOD-50241 | biostudies-arrayexpress
UnknownNetwork analysis of an OSCE-based graduation skills assessment for clinical medical students.
Not available
S-EPMC12023391 | biostudies-literature
UnknownTorsades de Pointes electrical storm in children with KCNH2 mutations.
Not available
S-EPMC11468024 | biostudies-literature
ProteomicsA comparative proteomic analysis of resistant and susceptible stylo against C. gloeosporioides reveals that SgATL31 is involved in disease resistance by promoting ROS burst
Stylo (Stylosanthes spp.) is a dominant leguminous forage, widely cultivated in tropical and subtropical areas. Anthracnose caused by Colletotrichum gloeosporioides is one of the most destructive diseases that limit the yield of stylo. Therefore, screening resistance varieties and improving the resi...
ORGANISM(S): Stylosanthes guianensis subsp. guianensis 
2025-07-14 | PXD059433 | Pride
Colletotrichum gloeosporioides Plasma membrane proteomics Evaluation of disease-resistant resources Sgatl31 Phosphoproteomics Stylosanthes 
ProteomicsPhosphoproteomic analysis of resistant and susceptible stylo against C. gloeosporioides
Stylo (Stylosanthes spp.) is a dominant leguminous forage, widely cultivated in tropical and subtropical areas. Anthracnose caused by Colletotrichum gloeosporioides is one of the most destructive diseases that limit the yield of stylo. Therefore, screening resistance varieties and improving the resi...
ORGANISM(S): Stylosanthes guianensis subsp. guianensis 
2025-07-14 | PXD059781 | Pride
Colletotrichum gloeosporioides Evaluation of disease-resistant resources Phosphoproteomics Stylosanthes 
TranscriptomicsAmitriptyline-mediated cognitive enhancement in aged 3xTg Alzheimer’s disease mice is associated with neurogenesis and neurotrophic activity
Approximately 35 million people worldwide suffer from Alzheimer’s disease (AD). Existing therapeutics, while moderately effective, are currently unable to stem the widespread rise in AD prevalence. AD is associated with an increase in amyloid beta (A) oligomers and hyperphosphorylated tau, along wit...
ORGANISM(S): Mus musculus 
2011-12-31 | E-GEOD-26836 | biostudies-arrayexpress
TranscriptomicsMultiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes
The central nervous system normally functions at O2 levels which would be regarded as hypoxic by most other tissues. However, most in vitro studies of neurons and astrocytes are conducted under hyperoxic conditions without consideration of O2-dependent cellular adaptation. We analyzed the reactivi...
ORGANISM(S): Rattus norvegicus 
2012-09-20 | E-GEOD-29296 | biostudies-arrayexpress
UnknownLncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
Not available
S-SCDT-10_1038-S44319-023-00030-4 | biostudies-other
ProteomicsLC-MS/MS identified the TRIM16-binding proteins
Vascular calcification (VC) is highly prevalent in patients with chronic kidney disease (CKD). To date, effective treatments for VC are still lacking since the underlying mechanisms remains elusive. RNA-sequencing analysis revealed that the E3 ubiquitin ligase Tripartite motif 16 (TRIM16) may be a k...
ORGANISM(S): Homo Sapiens 
2024-03-27 | PXD051036 |
ProteomicsLithocholic acid targets TULP3-Sirtuins to deacetylate v-ATPase and activate AMPK
Lithocholic acid (LCA), accumulated in mammals during calorie restriction (CR), can activate AMP-activated protein kinase (AMPK) and slow down ageing1. However, how LCA is signalled to activate AMPK and elicit the biological effects is unclear. Here, we show that LCA can enhance the activity of sirt...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD056134 |
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