Zhang Patrick H PH

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Unknown (10)
Transcriptomics (3)
Metabolomics (2)
Proteomics (1)

Organisms

Homo sapiens (4)

Repository

biostudies-arrayexpress (3)
MetaboLights (2)
pride (1)

Tissue

Cell culture (1)

Disease

Acute leukemia (1)

Technology Type

Mass spectrometry (1)
Mass spectrometry assay (1)
Mass Spectrometry (1)
Shotgun proteomics (1)

Instrument Platform

Liquid Chromatography MS - negative (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive (1)
Liquid Chromatography MS - positive - hilic (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2024 (2)
2013 (1)
2011 (1)
2008 (1)
2021 (1)

CHEBI ID

CHEBI:24809 (1)

Metabolite Name

(+)-Allopumiliotoxin 267A (1)
(+)-Eudesmin (1)
(-)-Lupinine (1)
(.+/-.)-Laudanosine (1)
(1R,2S)-1-(7,8-Dihydro-6-pteridinyl)-1,2-propanediol (1)
(1S,5R)-5-Isopropenyl-2-methyl-2-cyclohexen-1-yl beta-D-glucopyranoside (1)
(2E)-hexadecenoylcarnitine (1)
(2E,2'E)-3,3'-[2,4-Bis(1,3-benzodioxol-5-yl)-1,3-cyclobutanediyl]bis[1-(1-piperidinyl)-2-propen-1-one] (1)
(2R,5R,6R)-3-[(1E,3E)-hepta-1,3-dien-1-yl]-5,6-dihydroxy-2-(hydroxymethyl)cyclohexan-1-one (1)
(2S)-3-Hydroxy-2-({[(3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]methyl}amino)butanoic acid (non-preferred name) (1)
(2S)-3-Methyl-2-({[(3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]methyl}amino)butanoic acid (non-preferred name) (1)
(2S)-3-Phenyl-2-({[(3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]methyl}amino)propanoic acid (non-preferred name) (1)
(2S)-4-Methyl-2-({[(3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]methyl}amino)pentanoic acid (non-preferred name) (1)
(2S)-5-Carbamimidamido-2-(2-oxo-1-azetidinyl)pentanoic acid (1)
(4-Ethoxyphenyl)urea (1)
(4R)-4-{[(4R)-4-Hydroxy-1-methyl-L-prolyl]oxy}-1-methyl-L-proline (1)
(4S,5S,8S,10R)-4,5,8-trihydroxy-10-methyl-3,4,5,8,9,10-hexahydro-2H-oxecin-2-one (1)
(4S,5S,8S,10R)-4,5,8-trihydroxy-10-methyl-3,4,5,8,9,10-hexahydro-2H-oxecin-2-one*;*Hopantenic acid (1)
(5Z)-3-aminonon-5-enoic acid (1)
(5alpha,7alpha)-17-(Cyclopropylmethyl)-7-(2-hydroxy-3,3-dimethyl-2-butanyl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-yl beta-D-glucopyranosiduronic acid (1)
(6aR,11aR)-10-(3-Hydroxy-3-methylbutyl)-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene-3,9-diol (1)
(±)15-HETE (1)
.alpha.-Aminoadipic acid (1)
.alpha.-Glucoheptitol (1)
1,3,7-Trimethyluric acid (1)
1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate (1)
1,6-Dimethoxypyrene (1)
1-Methyl-2,3,4,9-tetrahydro-1H-beta-carboline-1,3-dicarboxylic acid (1)
1-Methyl-L-histidine*,*3-Methyl-L-histidine (1)
1-Nitrosopiperidine (1)

Study type

Transcription profiling by array (2)
RNA-seq of non coding RNA (1)

Release Date

2023 (4)
2025 (3)
2024 (2)
2013 (1)
2011 (1)
2008 (1)
2022 (1)

Lab affiliation

Translational Genomics Research Institute (1)

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A general non-self response as part of plant immunity

Plants, like other multicellular lifeforms, are colonized by microorganisms. How plants respond to their microbiota is currently not well understood. We used a phylogenetically diverse set of 39 endogenous bacterial strains from Arabidopsis thaliana leaves to assess host transcriptional and metaboli...

2021-09-13 | MTBLS2522 | MetaboLights

Burkholderia cenocepacia-mediated inhibition of Staphylococcus aureus growth and biofilm formation

Staphylococcus aureus asymptomatically colonizes the nasal cavity and pharynx of up to 60% of the human population and, as an opportunistic pathogen, can breach its normal habitat, resulting in life-threatening infections. S. aureus infections are of additional concern for populations with impair...

2024-11-26 | MTBLS11049 | MetaboLights

ATM regulates a DNA damage response post-transcriptional RNA operon in lymphocytes

Maintenance of genomic stability depends on the DNA damage response (DDR), a biological barrier in early stages of cancer development. Failure of this response results in genomic instability and high predisposition toward lymphoma, as seen in patients with ataxia-telangiectasia mutated (ATM) dysfunc...

ORGANISM(S): Homo sapiens

2011-01-05 | E-GEOD-25848 | biostudies-arrayexpress

Identification of transformation-related pathways in a breast epithelial cell model using a ribonomics approach.

Employing MCT-1 oncogene mediated transformation of immortalized breast epithelial MCF10A cells; we characterized the largely reciprocal association of these two RBPs with target mRNAs and their influence on protein expression vis-à-vis cellular transformation. Using a ribonomics approach, we ident...

ORGANISM(S): Homo sapiens

2008-07-29 | E-GEOD-12215 | biostudies-arrayexpress

Multicolor miRNA fluorescence in situ hybridization for tumor differential diagnosis

We profiled and quantitated miRNAs in two skin tumors (Basal cell carcinoma and Merkel cell carcinoma) and identified tumor-specific miRNAs. We used these tumor-specific miRNAs to guide development of miRNA fluorescence in situ hybridization. 2 barcoded sequencing runs, including 40 unique samples (...

ORGANISM(S): Homo sapiens

2013-06-28 | E-GEOD-34137 | biostudies-arrayexpress

Characterization of Arginine Methylation in Cancer Cell using LC-MS/MS

Protein arginine methyltransferase 9 (PRMT9) activity has been observed to be elevated in cancer patients, including many types of leukemias, correlating with poor prognosis and decreased response to immune checkpoint inhibitors. By targeting PRMT9, we can eliminate PRMT9-proficient/immune-cold canc...

ORGANISM(S): Homo sapiens (Human)

2024-01-11 | PXD039441 | Pride

Lc-ms/ms