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TranscriptomicsInducing pluripotency from mouse somatic cells by small-molecule compounds [RNA-Seq]
Pluripotent stem cells can be induced from somatic cells, providing an unlimited cell resource for regenerative medicine. However, genetic manipulation and difficult-to-manufacture strategies used in reprogramming limit their clinical applications. Here, we show pluripotency can be induced from mous...
ORGANISM(S): Mus musculus 
2013-07-22 | E-GEOD-48252 | biostudies-arrayexpress
TranscriptomicsBaseline and Post-Bortezomib gene expression profiling of CD138 purified bone marrow plasma cells from multiple myeloma patients
High PSMD4 expression levels in plasma cells are linked to poor prognosis in multiple myeloma. Additional file available-E-TABM-1138.additional.zip
ORGANISM(S): Homo sapiens 
2012-03-31 | E-TABM-1138 | biostudies-arrayexpress
ProteomicsMosaic PKHD1 variants in polycystic kidney caused aberrant protein profiling of mitochondria and lysosomes
Autosomal recessive polycystic kidney disease (ARPKD) is a severe renal cystic disease mainly caused by PKHD1. However, its genetic cause, pathological features, and mechanism remained unsolved. Our findings may provide new insight on the pathophysiology of the polycystic kidney due to PKHD1 deficie...
ORGANISM(S): Homo Sapiens 
2021-08-20 | PXD028042 |
TranscriptomicsInducing pluripotency from mouse somatic cells by small-molecule compounds [Phalanx Mouse OneArray]
Pluripotent stem cells can be induced from somatic cells, providing an unlimited cell resource for regenerative medicine. However, genetic manipulation and difficult-to-manufacture strategies used in reprogramming limit their clinical applications. Here, we show pluripotency can be induced from mous...
ORGANISM(S): Mus musculus 
2013-07-22 | E-GEOD-48201 | biostudies-arrayexpress
ProteomicsProteomic landscape of serum exosomes to identify potential therapeutic targets.
Using a tandem mass tag (TMT)-based quantitative proteomics approach, we characterized the proteomes of individual patient-derived serum exosomes, identified exosomal protein signatures specific to TNBC patients, and filtered out differentially expressed proteins.
ORGANISM(S): Homo Sapiens 
2021-08-04 | PXD027696 |
TranscriptomicsGeneration of murine stem cells by small molecule
Transcriptional profiling of stem cells and parental cells Two samples were analyzed: PEG cells and parental cells. Each sample have three replicates.
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-47102 | biostudies-arrayexpress
ProteomicsMolecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules
The production of secondary metabolites is one of the major mechanisms for beneficial rhizobacteria to antagonize plant pathogens. However, simultaneously producing large quantities of different secondary metabolites can pose great metabolic burdens and exerts a significant fitness cost on the produ...
ORGANISM(S): Pseudomonas Fluorescens F113 
PXD025403 |
ProteomicsComprehensive mass spectral libraries of human thyroid tissue and cells
We established deep-coverage thyroid-specific spectral libraries encompassing over 12,000 proteins, including samples from nine types of thyroid primary and lymph node metastases tissues and fifty thyroid cancer cell lines.
ORGANISM(S): Homo Sapiens 
PXD051051 |
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