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TranscriptomicsGenome wide profiling of HrpL-regulated genes in the necrotrophic plant pathogen Dickeya dadantii 3937
Background Dickeya dadantii is a necrotrophic pathogen causing disease in many plants. Previous studies have demonstrated that the type III secretion system (T3SS) of D. dadantii is required for full virulence. HrpL is an alternative sigma factor that binds to the hrp box promoter sequence of T3SS g...
ORGANISM(S): Dickeya dadantii 
2010-10-21 | E-GEOD-17185 | biostudies-arrayexpress
TranscriptomicsThe Impact of Carbon Source on Zymomonas mobilis 8b in the Presence of Acetate through Transcriptomic Analysis
Background: Lignocellulosic biomass is a promising renewable feedstock for the microbial production of fuels. To release the major fermentable sugars such as glucose and xylose, pretreatment and enzymatic hydrolysis of biomass feedstock are needed. During this process, many toxic compounds are produ...
ORGANISM(S): Zymomonas mobilis 
2014-09-08 | E-GEOD-57553 | biostudies-arrayexpress
ProteomicsThe proteome and phosphorylproteome of human early erythropoiesis
In order to revealed the multiple protein functional modules and kinases networks of human early erythropoiesis. We isolated the CD34+ cells drived from Human umbilical cord blood samples and induced to undergo erythropoiesis in vitro. Then, the cultured erythroid cells were sorted with FACS and sam...
ORGANISM(S): Homo Sapiens 
2022-08-03 | PXD035785 |
ProteomicsIdentification of GSDME-interacting proteins in HK-2 cells by immunoprecipitation-coupled LC-MS/MS analysis
This project aims to identify GSDME-associated proteins in human renal tubular epithelial (HK-2) cells using immunoprecipitation followed by LC-MS/MS. HK-2 cells overexpressing Flag-tagged GSDME were lysed, and protein complexes were enriched using anti-Flag antibody and Protein A/G magnetic beads. ...
ORGANISM(S): Homo Sapiens 
2025-04-12 | PXD062902 |
TranscriptomicsGenome-wide analysis of the genetic regulation of gene expression in human neutrophils
Here we report an expression dataset of isolated neutrophils from 114 healthy individuals of Chinese ethnicity collected in Singapore. A total of 114 individuals with no case control stratification.
ORGANISM(S): Homo sapiens 
2015-08-10 | E-GEOD-70044 | biostudies-arrayexpress
ProteomicsTargeting ubiquitin-independent proteasome with small molecule increases susceptibility in pan-KRAS mutant cancers
Despite advances in the development of direct KRAS inhibitors, KRAS-mutant cancers continue to exhibit resistance to the currently available therapies. Here, we identified REGγ as a mutant KRAS-associated factor that enhances REGγ transcription through the KRAS intermediate NRF2, suggesting that the...
ORGANISM(S): Homo Sapiens 
2025-01-01 | PXD059364 |
ProteomicsProteomics and Human Microchips Identify Thrombospondin-1 as a Potential Biomarker for Calciphylaxis Stem Cell Therapy
Calciphylaxis, also known as calcific uremic arteriolopathy (CUA), is a rare disease with high mortality rate. We effectively rescued CUA patients with novel human amnion-derived mesenchymal stem cell (hAMSC) therapy. Due to the heterogeneity of cutaneous lesion, it is imperative to identify non-inv...
ORGANISM(S): Homo Sapiens 
2026-05-14 | PXD078388 |
ProteomicsDissection of Blood Ecosystem in SARS-CoV-2 Omicron Patients
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD045174 |
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