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MetabolomicsHERPES SIMPLEX VIRUS TYPE 1 IMPAIRS DENDRITIC CELL FUNCTION BY REMODELLING NEUTRAL LIPID METABOLISM AND INDUCING LIPID DROPLET ACCUMULATION
Herpes simplex virus type 1 (HSV-1) infects dendritic cells (DCs), professional antigen-presenting cells that initiate and regulate host antiviral responses. HSV-1 infects DCs limiting their maturation, migration to draining lymph nodes and T cell activation capacity, ultimately promotes their apopt...
2025-04-03 | MTBLS5163 | MetaboLights
ProteomicsComparative exo-proteomic analysis of Trichoderma antagonists induced by oomycete mycelium highlights diverse antagonism strategies
Plant-beneficial fungi from the genus Trichoderma (Hypocreales, Ascomycota) can control oomyceteous plant-pathogenic Pythium myriotylum (Peronosporales, Oomycota) and thus serve as bioeffectors for the eco-friendly products of crop protection. However, the underlying mechanisms of microbe-microbe in...
ORGANISM(S): Trichoderma asperellum CBS 433.97 Trichoderma virens Gv29-8 Hypocrea jecorina (strain QM6a) (Trichoderma reesei) Trichoderma atroviride IMI 206040 Trichoderma parepimyces Trichoderma guizhouense 
2024-07-19 | PXD051895 | Pride
Trichoderma Exo-proteins Hydrolyase Antagonism 
GenomicNEIGHBOR Consortium Glaucoma GWAS

This is a case-control study of primary open angle glaucoma (POAG). POAG is an intraocular pressure (IOP) related progressive optic neuropathy that ultimately leads to blindness. For this study we have formed a collaborative consortium contributing 2170 POAG cases and 2347 controls with a unified...

phs000238 | dbGaP
UnknownKDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress.
Not available
S-EPMC10081958 | biostudies-literature
UnknownA novel regulatory circuit of ATG4B and SESN3 promotes T cell leukemogenesis.
Not available
S-EPMC12723951 | biostudies-literature
UnknownSuberoylanilide hydroxamic acid induces limited changes in the transcriptome of primary CD4(+) T cells.
Not available
S-EPMC3752851 | biostudies-literature
GenomicsGenome wide occupancy of Msgn1 in differentiating embryonic stem cells
Msgn1 is a bHLH transcription factor and is a direct target gene of the Wnt/b-catenin signaling pathway. During mouse embryogenesis, Msgn1 is expressed in the mesodermal compartment of the primitive streak and is required for the differentiation of presomitic mesoderm. Msgn1-/- mutants show defects ...
ORGANISM(S): Mus musculus 
2014-09-04 | E-GEOD-55263 | biostudies-arrayexpress
UnknownAberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver.
Not available
S-EPMC9243114 | biostudies-literature
TranscriptomicsTranscription profiling of human HEK293T to characterize CREB target genes in different tissue types
The CREB family of transcription factors stimulates cellular gene expression following phosphorylation at a conserved serine (Ser133 in CREB1) in response to cAMP and other extracellular signals. In order to characterize CREB target genes in various tissues, we give a cAMP agonist, forskolin (FSK), ...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2060 | biostudies-arrayexpress
GenomicsNational Eye Institute Glaucoma Human Genetics Collaboration (NEIGHBOR) Consortium Glaucoma Genome-Wide Association Study

This is a case-control study of primary open angle glaucoma (POAG). POAG is an intraocular pressure (IOP) related progressive optic neuropathy that ultimately leads to blindness. For this study we have formed a collaborative consortium contributing 2170 POAG cases and 2347 controls with a unified...

phs000238.v1.p1 | EGA
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