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UnknownrMVP: A Memory-efficient, Visualization-enhanced, and Parallel-accelerated Tool for Genome-wide Association Study.
Not available
S-EPMC9040015 | biostudies-literature
MetabolomicsMitochondrial Transplantation Ameliorates Doxorubicin-Induced Cardiac Dysfunction via Activating Glutamine Metabolism
Doxorubicin is a wildly used effective anticancer agent. However, doxorubicin use is also related to cardiotoxic side effect in some patients. Mitochondrial damage has been shown to be one of the pathogeneses of doxorubicin-induced myocardial injury. In this study, we test the hypothesis that mitoch...
2025-03-13 | MTBLS7989 | MetaboLights
ProteomicsComparative analysis of excretory–secretory products of muscle larvae of three isolates of Trichinella pseudospiralis by the iTRAQ method
we compared the differentially expressed proteins of excretory-secretory (ES) products in three isolates of T. pseudospiralis ML [muscle larvae from Russia (RUS), United States of America (USA) and Australia (AUS)] using isobaric tags for relative and absolute quantification (iTRAQ)-based technology...
ORGANISM(S): Trichinella pseudospiralis 
2020-05-07 | PXD017604 | Pride
Trichinella pseudospiralis Proteomics. Muscle larvae T cells Itraq Excretory-secretory products 
ProteomicsProteomic data of Stenotrophomonas maltophilia
S. maltophilia was exposed to a simulated microgravity (SMG) environment in high-aspect ratio rotating-wall vessels bioreactors for 14 days, while the control group was performed in the same bioreactors under normal gravity (NG) environment. After that, combined phenotypic, genomic, transcriptomic a...
ORGANISM(S): Stenotrophomonas maltophilia 
2021-04-30 | PXD025290 | Pride
Stenotrophomonas maltophilia  proteomic 
UnknownGenetic constraint at single amino acid resolution in protein domains improves missense variant prioritisation and gene discovery.
Not available
S-EPMC11238507 | biostudies-literature
TranscriptomicsTwo Supporting Factors Greatly Improve the Efficiency of Human iPS Cell Generation
Human fibroblasts can be induced into pluripotent stem cells (iPS cells), but the reprogramming efficiency is quite low. Here, we screened a panel of candidate factors in the presence of OCT4, SOX2, KLF4 and c-MYC in an effort to improve the reprogramming efficiency from human adult fibroblasts. We ...
ORGANISM(S): Homo sapiens 
2008-11-06 | E-GEOD-12922 | biostudies-arrayexpress
MetabolomicsThe gut microbiota contributes to changes in the host immune response induced by Trichinella spiralis
The gut microbiota plays an important role in parasite-host interactions and the induction of immune defense responses. Trichinella spiralis is an important zoonotic parasite that can directly or indirectly interact with the host in the gut. Changes in the gut microbiota following infection with T. ...
2023-08-07 | MTBLS7603 | MetaboLights
UnknownBasement membrane-associated gene P3H2 regulates osteosarcoma progression and epithelial-mesenchymal transition through AKT/mTOR signaling axis.
Not available
S-EPMC12637266 | biostudies-literature
ProteomicsProteome-Wide Deconvolution of Drug Targets and Binding Sites by Lysine Reactivity Profiling
Recently, numerous efforts have been devoted to identifying drug targets and binding sites in complex proteomes, which is of great importance in modern drug discovery. In this study, we developed a robust lysine reactivity profiling method to systematically study drug-binding targets and binding sit...
ORGANISM(S): Homo Sapiens 
2023-09-28 | PXD045749 |
Proteomics[HPP-2.0] Matrix Thermal Shift Assay for Fast Construction of Multidimensional Ligand–Target Space
Existing thermal shift-based mass spectrometry approaches are able to identify target proteins without chemical modification of the ligand, but they are suffering from complicated workflows with limited throughput. Herein, we present a new thermal shift-based method, termed matrix thermal shift assa...
ORGANISM(S): Homo Sapiens 
2023-09-29 | PXD045941 |
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