Sort   by:  
 Page size 
MetabolomicsMetabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM

Most of pre-diabetes were eventually progress to diabetes, thereby profiling of prediabetic metabolic disorders may be an effective targeted preventive measure. We aimed to elucidate internal motivation of the progression of pre-diabetes to type 2 diabetes mellitus (T2DM) from a metabolic perspec...

2024-04-29 | MTBLS8644 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
ProteomicsCircBIRC6-2 inhibits transmissible gastroenteritis virus induced mitochondrial permeability transition pore opening by its encoding protein
Transmissible gastroenteritis virus (TGEV), a member of coronavirus, is the pathogen of TGE. We previously found 123 circular RNAs (circRNAs) were differential expression during activation of mitochondrial permeability transition in porcine intestinal epithelial cells-jejunum 2 cell line (IPEC-J2) ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-10-13 | PXD029055 | Pride
Lc-ms/ms Peptide analysis Interacting protein 
ProteomicsHuman serum samples proteomic analysis
Vitamin D deficiency affected the abnormal protein expression, resulting in the abnormal activation of complement system.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036152 | Pride
Serum Proteomic Label-free Human 
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
TranscriptomicsThe Expression of MicroRNA and microRNA Clusters in the Aging Heart
Adult aging is a complex biological process associated with altered gene expression and a decline in physiological performance. The microRNAs have been implicated in cardiac development, cardiac hypertrophy and heart failure. However, the impact of adult aging on cardiac expression of both miRNA gui...
ORGANISM(S): Mus musculus 
2012-08-20 | E-GEOD-32935 | biostudies-arrayexpress
UnknownNext-generation sequencing for MRD monitoring in B-lineage malignancies: from bench to bedside.
Not available
S-EPMC9440501 | biostudies-literature
TranscriptomicsSRF Overexpression Leads to Altered Expression of MicroRNAs and Contributes to Cardiac Hypertrophy
The role of SRF in the regulation of microRNA expression and microRNA biogenesis in cardiac hypertrophy has not been well established. In this report, we employed a distinct transgenic mouse model to study the impact of SRF on cardiac microRNA expression and microRNA biogenesis. Cardiac-specific ove...
ORGANISM(S): Mus musculus 
2011-02-16 | E-GEOD-23044 | biostudies-arrayexpress
UnknownTNFRSF13B Variant-Induced TACI Dysregulation Underlies CAEBV Pathogenesis.
Not available
S-EPMC12830494 | biostudies-literature
UnknownCausal association of gut microbes and blood metabolites with acne identified through systematic mendelian randomization.
Not available
S-EPMC11538280 | biostudies-literature
Sort   by:  
 Page size