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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
ProteomicsGonatopoulos-Pournatzis _eIF4Gmicroexon_P105_Lumos
A This dataset consists of 24 raw MS files, acquired on Orbitrap Fusion Lumos Tribrid mass spectrometer operated in Data Dependent Acquisition mode. B Mouse samples were generated by Thomas Gonatopoulos-Pournatzis. Proteomics sample preparation and mass spectrometric acquisition was performed by Sh...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-12-04 | MSV000084658 | MassIVE
ProteomicsSsrp1 co-immunoprecipitation and mass spectrometry
Endogenous retroviruses (ERVs) were usually silenced by various histone modifications on histone H3 variants and respective histone chaperones in embryonic stem cells (ESCs). However, it is still unknown whether chaperones of other histones could repress ERVs. Here, we show that H2A/H2B histone chap...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-24 | PXD017351 | Pride
Ssrp1 Co-immunoprecipitation Mass spectrometry Esc 
ProteomicsProteome of follicular Fluid from lean and overweight/obese women with PCOS and that of healthy controls
Polycystic ovary syndrome (PCOS) is typically characterized by oligo or anovulation, hyperandrogenism and polycystic ovarian morphology, affecting 5-20% of women of reproductive age [1]. It has drawn significant attention as a major cause of anovulatory infertility and the syndrome of metabolic, rep...
ORGANISM(S): Homo sapiens (Human) 
2019-10-31 | PXD013937 | Pride
Human Pcos Tmt 
UnknownIn silico designed novel multi-epitope mRNA vaccines against Brucella by targeting extracellular protein BtuB and LptD.
Not available
S-EPMC10973489 | biostudies-literature
UnknownMaternal circulating exosomal miR-185-5p levels as a predictive biomarker in patients with recurrent pregnancy loss.
Not available
S-EPMC10033820 | biostudies-literature
UnknownDesign of a multi-epitope vaccine candidate against Brucella melitensis.
Not available
S-EPMC9202987 | biostudies-literature
UnknownPhytochemical Characterization, Antioxidant Activity, and Anti-Melanoma Mechanism of Flower Buds of <i>Magnolia biondii</i> Pamp.
Not available
S-EPMC12157075 | biostudies-literature
MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
UnknownA Machine Learning-Based Prediction Model for Acute Kidney Injury in Patients With Community-Acquired Pneumonia: Multicenter Validation Study.
Not available
S-EPMC11695953 | biostudies-literature
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