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UnknownLactylation of NAT10 promotes N4-acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivation.
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S-EPMC11445560 | biostudies-literature
ProteomicsThe changes in lysine acetylation levels of Bacillus altitudinis 6ww6 under salt stress
Applied the quantitative acetylome analysis technique to identify the up-regulated and down-regulated acetylation sites of proteins from Bacillus altitudinis under salt stress, and found that differentially acetylated proteins under salt stress mainly focused on energy generation and conversion, ami...
ORGANISM(S): Bacillus Altitudinis 
PXD056209 |
TranscriptomicsInducing pluripotency from mouse somatic cells by small-molecule compounds [RNA-Seq]
Pluripotent stem cells can be induced from somatic cells, providing an unlimited cell resource for regenerative medicine. However, genetic manipulation and difficult-to-manufacture strategies used in reprogramming limit their clinical applications. Here, we show pluripotency can be induced from mous...
ORGANISM(S): Mus musculus 
2013-07-22 | E-GEOD-48252 | biostudies-arrayexpress
TranscriptomicsGeneration of murine stem cells by small molecule
Transcriptional profiling of stem cells and parental cells Two samples were analyzed: PEG cells and parental cells. Each sample have three replicates.
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-47102 | biostudies-arrayexpress
ProteomicsIsolation and Comprehensive Analysis of Cochlear Tissue-derived Small Extracellular Vesicles
Label-free quantitative proteomics analysis of CDsEVs, with the same amount of protein of cochlear tissues used as the control
ORGANISM(S): Mus Musculus 
PXD056591 |
ProteomicsLoss of Drosophila nucleostemin 1 disrupts ribosomal protein homeostasis and rRNA processing to trigger apoptosis via the Xrp1/Irbp18 complex
In this study, we investigate the role of Ns1 in proliferating epithelial tissues using the Drosophila wing imaginal disc as a model. We demonstrate that knocking down Ns1 in wing discs leads to strong apoptosis. However, unlike the reported effect on overexpressed RPs, we did not observe nucleolar ...
ORGANISM(S): Drosophila Melanogaster 
2026-03-02 | PXD075076 |
ProteomicsIdentification of candidate microRNA biomarkers of endometriosis in different bodily fluids
Endometriosis is a common gynecological condition that affects approximately 10% of women of reproductive age and up to half of those experiencing infertility. However, there is a lack of reliable noninvasive diagnostic tools for diagnosing endometriosis. This study aims to identify novel biomarkers...
ORGANISM(S): Homo Sapiens 
2025-11-17 | PXD070868 |
ProteomicsDiverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules
Complex diseases often involve the interplay between genetic and environmental factors. Charcot-Marie-Tooth type 2 neuropathies (CMT2) are a group of genetically heterogeneous disorders, in which similar peripheral neuropathology is inexplicably caused by various mutated genes. Their possible molecu...
ORGANISM(S): Homo Sapiens 
2022-12-13 | PXD038754 |
ProteomicsCirculating Exosomes proteome of Colorectal Cancer Based on Rapid DIA-MS
Early screening is essential for the treatment of colorectal cancer (CRC). Concerns are rising regarding liquid biopsy due to its low invasiveness and reproducibility, especially when tissue samples are not available. Recent reports suggest that tumor-specific proteins may be stably expressed in exo...
ORGANISM(S): Homo Sapiens 
2019-10-20 | PXD015921 |
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