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ProteomicsThe proteomics sequencing of two engineered yeast strains CEN-Cho and CEN-Cho-MVA
An MS-based proteomics approach was utilized to monitor the changes in protein abundance between the CEN-Cho and CEN-Cho-mMVA. A total of 702 differently expressed proteins (DEPs) were identified in the comparison group.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-08-24 | PXD074200 | Pride
Proteomics analysis 
ProteomicsPhosphoproteomic analysis supporting structural basis for GABAA receptor pi activation
GABAA receptors (GABAAR) are pentameric chloride channels comprising various combinations of different subunits that are activated by γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in vertebrates. we show here that GABRP chloride channel activity and ERK signaling is directly regul...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD044482 | Pride
Phosphoproteomics Dia Gabaa receptor 
ProteomicsProteomics analysis of expi293 conditioned media purified with immobilized metal affinity chromatography
Isthmin-1 (ISM1) is a recently described adipokine with insulin-like properties, reported to regulate hyperglycemia and liver steatosis. However, contrary to earlier studies, we demonstrate that highly purified ISM1 does not stimulate AKT phosphorylation in 3T3-F442A pre-adipocytes. Instead, this ac...
ORGANISM(S): Homo sapiens (Human) 
2025-04-02 | PXD062353 | Pride
Dia Proteomics Akt 
ProteomicsProteomics analysis of blood neutrophils from WT and Wnt5 DKO mice under DSS treatment
Neutrophils are abundant innate immune cells with important roles in host defense and many inflammatory diseases. They possess plasticity and heterogenicity, which underlie their functional ambivalency; they can be beneficial or detrimental to host well-being depending on contexts. While bone marrow...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-16 | PXD048613 | Pride
Wnt5 Neutrophil Proteomics Dia 
ProteomicsGlycoprotein Signatures for Aggressive Prostate Cancer via SWATH mass spectrometry
The identification of biomarkers indicating the level of aggressiveness of prostate cancer (PCa) addresses an urgent clinical need to minimize the general over-treatment of patients with non-aggressive PCa, which account for the majority of PCa cases. In this study we combined N-glycopeptide isolati...
ORGANISM(S): Homo sapiens (Human) 
2014-04-23 | PXD000704 | Pride
Human Prostate Swath Glycoproteome 
Proteomicsphotoactivation-dependent proximity labeling (PDPL) MS
we report a photoactivation-dependent proximity labeling (PDPL) method designed by genetically attaching photosensitizer protein miniSOG to a protein of interest (POI). Triggered by blue light, singlet oxygen is generated, enabling temporally-resolved chemical probe labeling.
ORGANISM(S): Homo Sapiens 
2022-06-22 | PXD034811 |
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