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ProteomicsThe protection of Evodiamine against Ulcerative Colitis and Colorectal Cancer via anti-inflammation
Evodiamine (Evo), a kind of alkaloid mostly extracted from Tetradium ruticarpum, which has many pharmacological functions, such as antidiarrheal, antiemetic, and antiulcer effects. In this study, the effects of Evo were investigated in DSS-induced ulcerative colitis (UC) mice and C57BL/6-ApcMinC/Gpt...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD027745 | Pride
Colorectal cancer Inflammation Nf-κb Ulcerative colitis Evodiamine 
ProteomicsProteomics of Hsc70-interacting Proteins
we compared the interacting proteins between Hsc70-WT and Hsc70-3KA using mass spectrometry to discover additional mediators of this process
ORGANISM(S): Homo Sapiens 
2024-04-05 | PXD051241 |
ProteomicsARIH1 Signaling Promotes Anti-tumor Immunity by Targeting PD-L1 for Proteasomal Degradation
We find EGFR inhibitors promote PD-L1 ubiquitination and proteasomal degradation following GSK3α-mediated phosphorylation of Ser279/Ser283.
ORGANISM(S): Homo Sapiens 
2021-03-01 | PXD024452 |
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