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UnknownCharacterization of miRNA profiles in the mammary tissue of dairy cattle in response to heat stress.
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S-EPMC6309072 | biostudies-literature
ProteomicsSpatiotemporal dog brain proteome
The complexity and low accessibility of the human brain make it challenging to understand its development, function, and disorders. Brain diseases including neurodegenerative disease and psychiatric diseases incur huge medical and social burdens without effective treatments. While mouse has substant...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-08-12 | PXD034449 | Pride
Brain Multiple regions Proteome Canine 
ProteomicsSpatiotemporal dog brain proteome
The complexity and low accessibility of the human brain make it challenging to understand its development, function, and disorders. Brain diseases including neurodegenerative disease and psychiatric diseases incur huge medical and social burdens without effective treatments. While mouse has substant...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-08-12 | PXD033420 | Pride
Brain Multiple regions Proteome Canine 
ProteomicsMonolaurin confers a protective effect against porcine epidemic diarrhea virus infection in piglets by regulating the interferon pathway
Porcine epidemic diarrhea virus (PEDV) has reemerged as the main pathogen of piglets due to its high mutation feature. Monolaurin (ML) is a natural compound with a wide range of antibacterial and antiviral activities. However, the role of ML in PEDV infection is still unknown. This study aimed to ev...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-16 | PXD029561 | Pride
Infection. Interferon Monolaurin Piglets Porcine epidemic diarrhea virus 
TranscriptomicsClaudin-7 is frequently overexpressed in ovarian cancer and promotes invasion
Claudins are tight junction proteins that are involved in tight junction formation and function. Previous studies have shown that claudin-7 is frequently upregulated in epithelial ovarian cancer (EOC) along with claudin-3 and claudin-4. Here, we investigate in detail the expression patterns of claud...
ORGANISM(S): Homo sapiens 
2012-09-19 | E-GEOD-26055 | biostudies-arrayexpress
TranscriptomicsToll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia
Microglia are the resident mononuclear phagocytes of the CNS parenchyma and represent an initial line of defense against invading microorganisms. Microglia utilize Toll-like receptors (TLRs) for pathogen recognition and TLR2 specifically senses conserved motifs of gram-positive bacteria including li...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-24935 | biostudies-arrayexpress
TranscriptomicsChanges in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury
Warfare has long been associated with traumatic brain injury (TBI) in militarized zones. Common forms of TBI can be caused by a physical insult to the head-brain or by the effects of a high velocity blast shock wave generated by the detonation of an explosive device. While both forms of trauma are d...
ORGANISM(S): Mus musculus 
2013-03-18 | E-GEOD-44625 | biostudies-arrayexpress
TranscriptomicsThe effect of short term Rapamycin on the transcriptome of old mouse liver
Analysis of the effect of gene expression in the livers of old mice (25 months of age) fed rapamycin short term (6 months) Rapamycin from 19 months of age. Total RNA extracted from livers of 25 month old C57BL6/N male and female mice started on control or 14 ppm rapamycin (Rapa) from 19 months of ag...
ORGANISM(S): Mus musculus 
2014-02-07 | E-GEOD-48331 | biostudies-arrayexpress
TranscriptomicsThe effect of chronic Rapamycin on the transcriptome of old mouse liver
Analysis of the effect of gene expression in the livers of old mice (25 months of age) fed rapamycin chronically (21 months) from 4 months of age. Total RNA extracted from livers of 25 month old C57BL6/J male and female mice started on control or 14 ppm rapamycin (Rapa) from 4 months of age on 21 mo...
ORGANISM(S): Mus musculus 
2014-02-07 | E-GEOD-48333 | biostudies-arrayexpress
TranscriptomicsThe effect of Rapamycin on the transcriptome of old mouse liver
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-02-07 | E-GEOD-48334 | biostudies-arrayexpress
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