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ProteomicsHuman Plasma Proteome by Isobaric Tags for Relative and Absolute Quantitation Based Quantitative Proteomics Technique
This project was to identify relevant diagnostic biomarkers for vascular aging by performing a targeted proteomic comparison of plasma proteins between aortic stiffness (high PWV) and non-aortic stiffness (normal PWV) populations using isobaric tags for relative and absolute quantitation based qua...
ORGANISM(S): Homo Sapiens 
2021-12-19 | PXD030531 |
ProteomicsCardiomyocyte-derived GPX4 stabilizes BNIP3 to facilitate mitophagy and mitigate myocardial ischemia/reperfusion injury
To elucidate the molecular mechanisms by which GPX4 regulates mitochondrial function, we overexpressed GPX4 in cardiomyocytes and subjected them to hypoxia-reoxygenation (H/R) modeling. Co-immunoprecipitation (Co-IP) coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was employed...
ORGANISM(S): Mus Musculus 
2025-12-22 | PXD072382 |
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