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TranscriptomicsmRNA expression in blood of 18 schizophrenia patients and 12 healthy controls
The study profiles genome-wide mRNA expression in blood from 18 early-onset SZ (EOS) cases and 12 healthy controls. A total of 1070 mRNAs were detected by the microarrays in our samples. 18 schizophrenia samples and 12 healthy controls were used to acquire blood expression profiles
ORGANISM(S): Homo sapiens 
2014-12-05 | E-GEOD-54913 | biostudies-arrayexpress
TranscriptomicsExpression in blood of schizophrenia patients and healthy controls
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-12-05 | E-GEOD-54914 | biostudies-arrayexpress
UnknownConverging evidence implicates the abnormal microRNA system in schizophrenia.

Background

Previous findings are inconsistent; yet, converging evidence suggests an association between schizophrenia (SZ) and the impairment of posttranscriptional regulation of brain development through microRNA (miRNA) systems.

Methods

This study aims to (1) compare the overall fre...
S-EPMC4393688 | biostudies-literature
UnknownPrediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis.

Background

Choosing the appropriate antipsychotic drug (APD) treatment for patients with schizophrenia (SCZ) can be challenging, as the treatment response to APD is highly variable and difficult to predict due to the lack of effective biomarkers. Previous studies have indicated the associati...
S-EPMC10236828 | biostudies-literature
UnknownPromotion of Lung Cancer Metastasis by SIRT2-Mediated Extracellular Protein Deacetylation.
Acetylation of extracellular proteins has been observed in many independent studies where particular attention has been given to the dynamic change of the microenvironmental protein post-translational modifications. While extracellular proteins can be acetylated within the cells prior to their micro...
S-EPMC9875677 | biostudies-literature
UnknownChemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline (updated version).
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the world. Diagnosis and treatment guidelines for clinicians caring for patients are needed. In...
S-EPMC7472403 | biostudies-literature
UnknownContinual Decline in Azole Susceptibility Rates in Candida tropicalis Over a 9-Year Period in China.

Background

There have been reports of increasing azole resistance in Candida tropicalis, especially in the Asia-Pacific region. Here we report on the epidemiology and antifungal susceptibility of C. tropicalis causing invasive candidiasis in China, from a 9-year surveillance st...
S-EPMC8299486 | biostudies-literature
UnknownUltrahigh-energy gamma-ray emission associated with black hole-jet systems.
Black holes (BHs), one of the most intriguing objects in the universe, can manifest themselves through electromagnetic radiation initiated by the accretion flow. Some stellar-mass BHs drive relativistic jets when accreting matter from their companion stars, forming microquasars. Non-thermal emission...
S-EPMC12746838 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownRobust estimation of bacterial cell count from optical density.
Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-...
S-EPMC7499192 | biostudies-literature
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