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TranscriptomicsExpression analysis of Streptomyces avermitilis NRRL8165 delta-aveI mutant
Investigation of whole genome gene expression level changes in Streptomyces avermitilis delta-aveI mutant, compared to the wild-type strain. The mutants analyzed in this study are further described in Chen L, Lu Y., Chen J, Zhang W, Shu D, Qin Z, Yang S, Jiang W. (2008) Characterization of a negativ...
ORGANISM(S): Streptomyces avermitilis 
2010-05-16 | E-GEOD-16892 | biostudies-arrayexpress
MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
ProteomicsComputational prediction combined with proteogenomics unveils widespread non-AUG translation initiation events in plants
Non-AUG translation initiation is crucial for regulating translation, which can generate N-terminally extended protein isoforms with diverse biological functions. However, a comprehensive view of non-AUG translation initiation events with N-terminal extensions (NTEs) across monocots and dicots remai...
ORGANISM(S): Glycine max Zea mays (Maize) Oryza sativa (Rice) 
2026-04-27 | PXD058528 | Pride
Non-aug translation initiation  n-terminally extended protein isoforms  n-terminal extensions (ntes)  upstream translation initiation sites (utiss)  proteogenomics  monocots and dicots 
UnknownPulsed electromagnetic fields modulate energy metabolism during wound healing process: an in vitro model study.
Not available
S-EPMC11823022 | biostudies-literature
UnknownConvalescent plasma may be a possible treatment for COVID-19: A systematic review.
Not available
S-EPMC7833727 | biostudies-literature
ProteomicsProteomics analysis reveals the effect of Aeromonas hydrophila sirtuin CobB on biological functions
a DIA-based proteomics method was used to compare the differently protein abundance between cobB deleted mutant and wild type strain.
ORGANISM(S): Aeromonas Hydrophila 07-345-3437 
2020-12-31 | PXD023330 |
ProteomicsProteomics analysis reveals the importance of transcriptional regulator slyA in regulation of diverse physiological functions in Aeromonas hydrophila
Proteomics analysis reveals the importance of transcriptional regulator slyA in regulation of diverse physiological functions in Aeromonas hydrophila
ORGANISM(S): Aeromonas Hydrophila Subsp. Hydrophila Atcc 7966 
2022-10-27 | PXD023117 |
ProteomicsAffinity purification of TRMT6/61A protein complexes
In order to identify the molecular mechanism leading to the increase of TRMT6/61A complex in aged HSCs, we purified proteins interacting with TRMT6 and TRMT61A via affinity purification. HEK293T cells stably expressing SFB-tagged TRMT6 or SFB-TRMT61A were lysed in NETN buffer (20 mM Tris-HCl [pH 8.0...
ORGANISM(S): Homo Sapiens 
2023-11-30 | PXD047430 |
ProteomicsFunctional Optic Tract Rewiring via Subtype- and Target-specific Axonal Regeneration and Presynaptic Activity Enhancement
We showed that with genetic manipulation as Pten/Socs3 knockout (KO), CNTF overexpression and Lipin1 knockdown (PSCL), RGCs could regenerate and reinnervate into OPN nuclei after pre-OPN optic tract injury. We then performed single-cell RNA sequencing on OPN-projecting retinal ganglion cells and pro...
ORGANISM(S): Mus Musculus 
PXD052573 |
ProteomicsLow-dose metformin targets the lysosome-AMPK pathway through PEN2
Metformin is the most prescribed anti-diabetic medicine, and has also been shown to have other various benefits, such as anti-aging and anti-cancer effects. For clinical doses of metformin, it is known that AMPK plays a major role; however, the direct molecular target of metformin remains unclear. H...
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-01 | PXD030090 |
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