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TranscriptomicsChip-on-chip analysis of direct Nkx2.1 target genes in proliferating and differentiating epithelium in mouse lung development.
Nkx2.1 is a critical regulator of mammalian lung development. It is expressed in epithelial cells at the initiation of lung organogenesis, becoming progressively restricted during development to bronchiolar and alveolar type II epithelial cells. In humans, it is a common marker of carcinomas of lung...
ORGANISM(S): Mus musculus 
2011-11-01 | E-GEOD-23043 | biostudies-arrayexpress
TranscriptomicsAssociation of genes regulated by Ezh2 and trimethylation of histone 3 lysine 27
Differentiation of naïve CD4+ T cells into effector (Th1, Th2 and Th17) and induced regulatory (iTreg) T cells requires lineage-specifying transcription factors and epigenetic modifications that allow appropriate repression or activation of gene transcription. The epigenetic silencing of cytokine ge...
ORGANISM(S): Mus musculus 
2014-08-04 | E-GEOD-57500 | biostudies-arrayexpress
ProteomicsOligodendrocyte precursor cell-specific blocking of low glucose-induced activation of AMPK ensures myelination and remyelination
In this study, we screening the main types of cerebral cortex cells for glucose sensing and have find that AMPK is not activated in OPCs. We further discover that aldolase C (ALDOC) is acetylated at K14 in OPCs. Expression of ALDOC-K14R, with the acetylation lysine residues changed to arginine, rend...
ORGANISM(S): Rattus Rattus Homo Sapiens 
2025-08-13 | PXD067336 |
ProteomicsThe proteomics of Candida albicans
The proteomics of different isolates of Candida albicans
ORGANISM(S): Candida Albicans 
2022-03-07 | PXD032114 |
ProteomicsProteomic analysis of linear ubiquitination substrates based on NAEK-Ub probe in live cells
While linear ubiquitin plays critical roles in multiple cell signaling pathways, few substrates have been identified. Global profiling of linear ubiquitin substrates represents a significant challenge because of the low endogenous level of linear ubiquitination, the none-specific binding of linear p...
ORGANISM(S): Homo Sapiens 
2022-02-11 | PXD031600 |
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