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Recent studies have identified a Lys 27-to-methionine (K27M) mutation at one allele of H3F3A, one of the two genes encoding histone H3 variant H3.3, in 60% of high-grade pediatric glioma cases. The median survival of this group of patients after diagnosis is ∼1 yr. Here we show that the levels of H3...
ORGANISM(S): Homo sapiens 
abundance based on iBAQ with SILAC, Interaction consistency score: 20.0, Coverage: 35
ORGANISM(S): 9544 
2018-00-00 | 1498921887 | PAXDB
PIWI-interacting small RNAs (piRNAs) protect the germline genome and are essential for fertility. Previously, we showed that ribosomes guide the biogenesis of piRNAs from long non-coding RNAs (lncRNAs) after translating the short open reading frames (ORFs) near their 5′ cap. It remained unclear, how...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-17 | PXD027489 | Pride
Chromatin-based epigenetic memory relies on the equal distribution of parental histone tetramers, which serve as templates for duplicating parental chromatin, to newly synthesized daughter DNA strands. Histone chaperones within the replisome, such as the histone binding domains (HBDs) of Mcm2 and Po...
ORGANISM(S): Schizosaccharomyces Pombe (ncbitaxon:4896) 
2023-07-16 | MSV000092452 | MassIVE
By comparing mRNA profiles of the two groups of bee larvae (treated by miR-184 and water), we found that there were 279 mRNAs which were differently expressed between treated and control larvae (ratio>2 and p<0.01), of which 200 mRNAs were down-regulated in treated larvae, and 79 mRNAs were down-reg...
ORGANISM(S): Apis mellifera 
Social caste determination in the honey bee is assumed to be determined by the dietary status of the young larvae and translated into physiological and epigenetic changes through nutrient-sensing pathways. We have employed Illumina/Solexa sequencing to examine the small RNA content in the bee larval...
ORGANISM(S): Apis mellifera 
Comparative Proteome Analysis of Four Sorghum Varieties Response to PEG Stress
ORGANISM(S): Sorghum Bicolor X Saccharum Hybrid Cultivar 
2022-05-12 | PXD033820 |
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