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MetabolomicsMetabolomics Study of Serum and Urine Samples Reveals Metabolic Pathways and Biomarkers Associated with Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is a common medical condition among women and involves complicated diagnostics and controversial surgical management. The exact molecular mechanism underlying POP is poorly understood, especially at the metabolism level. To explore the metabolic mechanism underlying POP a...
2019-08-14 | MTBLS1033 | MetaboLights
ProteomicsTMT-Based Quantitative Proteomic Analysis of Intestinal Or-ganoids Infected by Listeria monocytogenes with Different Virulence
L. monocytogenes consisting of 13 serotypes, is an opportunistic food-borne pathogen that causes different host reactions to depend on its serotypes. In this study, highly toxic L. monocytogenes 10403s resulted in more severe infections and lower survival rates. Additionally, to investigate the remo...
ORGANISM(S): Mus Musculus 
2022-05-27 | PXD034151 |
ProteomicsProteomic analysis of TMT of sea urchin(Strongylocentrotus intermedius) under high temperature stress
In order to investigate the protein expression of S. intermedius under high temperature stress. The study was conducted with the high-temperature resistant strain of S. intermedius and the control group of S. intermedius.
ORGANISM(S): Strongylocentrotus Intermedius 
2023-07-18 | PXD043884 |
ProteomicsPDZ domain-containing adaptor protein GIPC1 interacts with the SR-B1 and modulates its expression and lipid transport function
PDZ family protein GIPC1 physically interacts with SR-B1 and regulates SR-B1 expression by promoting SR-B1 protein stability.
ORGANISM(S): Mus Musculus 
2021-03-09 | PXD024595 |
ProteomicsChromatin-associated OGT promotes hepatocellular carcinoma malignancy via activating ZNF263
OGT, the only facilitator which attaches the monosaccharide to many oncogenic factors or tumor suppressors, has been suggested to play an influential role in tumorigenesis and metastasis of HCC. OGT interactome analyses indicates that disordered OGT may serve as a hub protein to activate the buildin...
ORGANISM(S): Homo Sapiens 
2023-01-12 | PXD039365 |
ProteomicsIdentification of TRADD phosphorylation sites
We re-introduced Flag-mTRADD into Tradd-/- MEFs, and identified the phosphorylation sites of TRADD which were induced by TNF and inhibited by TAK1 inhibitor 5Z7 using mass spectrometry. We found that TAK1 could mediate the phosphorylation of multiple sites in TRADD upon TNF stimulation. We next perf...
ORGANISM(S): Homo Sapiens 
2024-10-05 | PXD056588 |
ProteomicsArrestin engagement of the metabotropic glutamate receptor mGlu5
Phosphorylation sites identified at the C-terminus of mGlu5 by mass spectrometry analysis
ORGANISM(S): Homo Sapiens 
2026-04-01 | PXD076479 |
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