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TranscriptomicsThyroid deficiency before birth modifies adipose transcriptome to promote overgrowth of white adipose tissue and impair thermogenic capacity
This study investigates the development of adipose tissue before birth which is crucial for energy storage and thermogenesis in the neonatal period, and for long term metabolic health. The design uses the thyroid deficiency sheep fetus examined at two different gestational ages.
ORGANISM(S): Ovis aries 
2020-03-31 | E-MTAB-8396 | biostudies-arrayexpress
UnknownUSPoint: Self-Supervised Interest Point Detection and Description for Ultrasound-Probe Motion Estimation During Fine-Adjustment Standard Fetal Plane Finding.
Not available
S-EPMC7614558 | biostudies-literature
ProteomicsTracheal aspirate proteome from hospitalized patients infected with SARS-CoV-2
Tracheal aspirate was collected from intubated patients with SARS-CoV-2 infections or for reasons not related to COVID-19 (controls). The proteins were extracted using the MPLEx method. Proteins were digested with trypsin and analyzed by LC-MS/MS on a Thermo Q Exactive HF-X. Data was searched with M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-06 | MSV000089614 | MassIVE
ProteomicsPrP concentration in the central nervous system: regional variability, genotypic effects, and pharmacodynamic impact
Prion protein (PrP) concentration controls the kinetics of prion replication and is a genetically and pharmacologically validated therapeutic target for prion disease. In order to evaluate PrP concentration as a pharmacodynamic biomarker and assess its contribution to known prion disease risk factor...
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
2022-02-28 | PXD031432 | panorama
TranscriptomicsLenalidomide-mediated enhanced translation of C/EBP?-p30 protein upregulates expression of the anti-leukemic microRNA-181a in acute myeloid leukemia - microRNA Data
Recently, we showed that increased miR-181a expression was associated with improved outcomes in cytogenetically normal acute myeloid leukemia (CN-AML). Interestingly, miR-181a expression was increased in CN-AML patients harboring CEBPA mutations, which are usually biallelic and associate with better...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-MTAB-1320 | biostudies-arrayexpress
UnknownSenSet defines cell-type specific senescence signatures in the aged human lung
Not available
S-SCDT-10_1038-S44318-026-00762-8 | biostudies-other
UnknownThe effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Not available
S-EPMC3145073 | biostudies-literature
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