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ProteomicsDIA-Based Quantitative Proteomic Analysis of Early and Late Endosomes in A549 Cells Following Amphotericin B Pretreatment and Influenza A Virus Infection
Amphotericin B (AmB) is a polyene macrolide antifungal agent that binds to ergosterol, disrupting fungal membranes through lipid interactions. However, its effects on host cell protein composition remain unclear. In this study, A549 cells were pretreated with AmB prior to infection with the influenz...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD064637 | Pride
Amphotericin b  influenza a virus  endosome  dia proteomics 
ProteomicsBrucella suis S2 strain inhibits IRE1/Caspase-12/Caspase-3 pathway-mediated apoptosis of microglia HMC3 by affecting the ubiquitination of CALR
Neurobrucellosis is a serious complication of brucellosis, which poses a significant threat to human health and quality of life. The origin of this phenomenon is that the patients are more vulnerable to the development of chronic Brucella infection, which is also an important clinical problem. The r...
ORGANISM(S): Homo sapiens (Human) 
2025-02-20 | PXD056006 | Pride
Neurobrucellosis  brucella suis s2  endoplasmic reticulum stress  microglia  apoptosis 
ProteomicsTemozolomide Induces Glioblastoma Dedifferentiation into Highly Malignant Stem-like Cells Through Senescence-Associated Reprogramming via HIF1α/HIF2α Regulation
A critical issue is that recurrent glioblastoma multiforme (GBM) after temozolomide (TMZ) exposure becomes more malignant, exhibiting higher invasion and stemness than the primary tumor. However, the detailed mechanism remains to be elucidated. While the majority of GBM cells succumb to TMZ treatmen...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058156 | Pride
Temozolomide Glioblastoma 
UnknownGenome-Wide Detection of Major and Epistatic Effect QTLs for Seed Protein and Oil Content in Soybean Under Multiple Environments Using High-Density Bin Map.
Not available
S-EPMC6412760 | biostudies-literature
MetabolomicsAlterations in the Gut Microbiota and Metabolomics of Seafarers after a Six-Month Sea Voyage

Maintaining the health of seafarers is a difficult task during long-term voyages. Little is known about the corresponding changes in the gut microbiome-host interaction. This study recruited 30 seafarers undertaking a 6-month voyage and analyzed their gut microbiota using 16S rRNA gene sequencing...

2022-09-29 | MTBLS5335 | MetaboLights
UnknownTCTP promotes glioma cell proliferation in vitro and in vivo via enhanced β-catenin/TCF-4 transcription.
Not available
S-EPMC3895383 | biostudies-literature
TranscriptomicsRice Transcriptome - Slide A; Slide B
[Oryza sativa Genome Oligo Set Version 1.0 was designed by Beijing Genomics Institute (BGI) and contain 60,727 70mer oligos representing both indica and japonica genomes. All oligos were designed from cDNAs, expreseed sequence tag (EST) sequences, predicted genes of BGI rice genome build and other p...
ORGANISM(S): Oryza sativa (indica cultivar-group) 
2010-06-10 | E-GEOD-2691 | biostudies-arrayexpress
ProteomicsJEV Infected BV2 Cells with Proteomics
We sought to paint a panoramic picture of JEV-infected BV2 cells. High depth TMT labelling for quantitative proteomics was used to assess JEV infection with BV2 and compared immune response profiles at 6h, 12h, and 24h post-infection (hpi).According to gene ontology and KEGG enrichment analysis, imm...
ORGANISM(S): Mus musculus (Mouse) 
2022-09-09 | PXD033575 | Pride
Jev mouse proteomics 
UnknownRealizing real-time optical molecular imaging in peripheral nerve tissue via Rhodamine B.
Not available
S-EPMC11628308 | biostudies-literature
UnknownSafety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or -naive melanoma.
Not available
S-EPMC3837092 | biostudies-literature
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