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ProteomicsHuman HNF1A KI mice liver proteome analysis
Nonalcoholic fatty liver disease (NAFLD) is a pathological condition caused by excessive fat accumulation in liver. HNF1A is the pathogenic cause of hepatocellular adenoma and HCC. It is an important transcription factor in liver. We constructed a knock-in mice expressing a human dominant negative H...
ORGANISM(S): Mus Musculus 
2023-03-02 | PXD040561 |
ProteomicsHierarchical Helical Carbon Nanotube Fibre as a Bone Integrating ACL Replacement
Hierarchically assembled helical fiber integrates effectively with bones
ORGANISM(S): Oryctolagus Cuniculus Homo Sapiens 
2023-03-17 | PXD032128 |
ProteomicsLC-MS Results of Velvet Antler
This study aimed to investigate the constituents of Velvet Antler by Liquid Chromatography-Mass Spectrometry.
ORGANISM(S): Cervus Nippon 
2018-11-30 | PXD011912 |
ProteomicsProteogenomic Characterization of Skull-base Chordoma
Skull-base chordoma (SBC) is a rare, aggressive bone cancer with a high recurrent rate. Genomic studies of SBC have improved our understanding of the disease’s biology. However, the molecular biological characteristics and the effective therapy of SBC remain unknown. Here, we carried out an integrat...
ORGANISM(S): Homo Sapiens 
2024-07-01 | PXD053550 |
ProteomicsProteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic Targets
In this study, we performed integrated multi-omics analyses using genomic (n = 79), transcriptomic (n = 42), proteomic (n = 224), and phosphoproteomic (n = 49) data collected from 224 samples from 168 patients with malignant and benign breast diseases. Our data revealed the characteristics of the li...
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD040750 |
ProteomicsProteogenomics of urothelial bladder cancer progression reveals the distinguished molecular features of different pathological subtypes
We reported a comprehensive proteogenomics analysis, including whole-genome sequencing, RNA sequencing, and proteomics and phosphoproteomics profiling, of 448 trace-tumor-samples from 190 urothelial bladder neoplasm patients, covering the whole spectrum of disease stages and grades. DNA damage was a...
ORGANISM(S): Homo Sapiens 
2023-08-02 | PXD043775 |
ProteomicsCell fate decision by a morphogen-transcription factor-chromatin modifier axis
The IP-MS data includes SALL4 IP-MS data with or without BMP4 treatment at day 3 of JGES reprogramming, each group contain 3 repeats.
ORGANISM(S): Mus Musculus 
2024-04-12 | PXD051433 |
ProteomicsIntegrated Proteogenomic Characterization across Major Histological Types of Pituitary Neuroendocrine Tumors
Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors. Due to its extensive tumor heterogeneity and the lack of high-quality tissues for biomarker discovery, the causative molecular mechanisms are far from being fully defined. Therefore, more studies are needed to imp...
ORGANISM(S): Homo Sapiens 
2022-10-17 | PXD031467 |
ProteomicsSingle-cell transcriptome atlas reveals the underlying mechanism of kynurenic acid in regulation tumor immune microenvironment in glioblastoma
We performed 4D-DIA approach to quantified the proteome of GBM tissues from two groups. An average of 8880 quantified proteins were identified in each sample. In order to further explore the regulation of Kyna on GMB-resident T cells at the protein level, we performed 4D-DIA proteome analysis of CD4...
ORGANISM(S): Mus Musculus 
2025-10-30 | PXD070137 |
ProteomicsProteogenomics of diffuse gliomas reveal molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms
This dataset include the proteomic data of 243 glioma tumor tissues (discovery: 187, validation: 56); 56 tumor-adjacent tissues (discvoery: 35, validation: 21); 12 normal brain tissues; corresponding phosphoproteomic data
ORGANISM(S): Homo Sapiens 
2022-12-12 | PXD038732 |
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