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Profibrotic proximal tubular (PT) were identified as a unique phenotype of PTCs in renal fibrosis by single-cell RNA sequencing (scRNA-seq). Controlling the process of renal fibrosis requires understanding how to manage the S1 subset's branch to the S3 subset rather than to the profibrotic PT sub...

2024-05-28 | MTBLS9985 | MetaboLights
we conducted immunoprecipitation (IP) in UMUC3 and T24 cells using FKBP10 and Flag antibodies, followed by mass spectrometry analysis.
ORGANISM(S): Homo Sapiens 
To characterize the accessibility of α-syn to LPC and DOPS, we performed cross-linking experiments coupled with mass spectrometry (XL-MS). We mixed 15N-labeled and unlabeled Ac-α-syn at a 1:1 ratio and selected the cross-linked fragments containing both 15N-labeled and unlabeled Ac-α-syn to map the ...
ORGANISM(S): Homo Sapiens 
2024-12-26 | PXD059259 |
We performed affinity purification of PRRX1 using cells expressing Flag tagged PRRX1 isoforms - PRRX1A or PRRX1B, and carried out mass spectrometry (AP-MS) analysis.
ORGANISM(S): Homo Sapiens 
Tyrosine phosphorylation, orchestrated by tyrosine kinases and phosphatases, modulates a multi-layered signaling network in a time and space dependent manner. Dysregulation of this post-translational modification is inevitably associated with pathological diseases. Our previous work has demonstrated...
ORGANISM(S): Homo Sapiens 
2020-10-19 | PXD022084 |
Zinc is an essential trace element that is closely related to learning and memory ability. The hippocampus plays an important role in learning and memory and has the highest zinc concentration in the brain. Severe zinc deficiency (zinc-deprived diet) significantly alter hippocampal protein expressio...
ORGANISM(S): Rattus Norvegicus 
SEPHS2, a key enzyme in synthesizing selenoproteins, which converts hydrogen selenide into selenophosphate. Here we provide the proteome of SEPHS2 knockout human A375 celllines.
ORGANISM(S): Homo Sapiens 
2026-03-25 | PXD076137 |
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