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UnknownThe construction and analysis of ceRNA network and patterns of immune infiltration in lung adenocarcinoma.

Background

Competitive Endogenous RNA (ceRNA) may be closely associated with tumor progression. However, studies on ceRNAs and immune cells in LUAD are scarce.

Method

The profiles of gene expression and clinical data of LUAD patients were extracted from the TCGA database. Bioinformati...
S-EPMC8594182 | biostudies-literature
ProteomicsComprehensive proteomic analysis reveals distinct features and diagnostic biomarker panel for early pregnancy loss in histological subtypes
Early pregnancy loss (EPL) is a common event in human reproduction and is classified into histological subtypes such as hydropic abortion (HA) and hydatidiform moles, including complete hydatidiform moles (CHMs) and partial hydatidiform moles (PHMs). However, accurate diagnosis and improved patient ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD053739 | Pride
Proteomic Hydatidiform mole Early pregnancy loss Precious diagnosis Biomarkers 
ProteomicsComprehensive proteomic analysis reveals distinct features and diagnostic biomarker panel for early pregnancy loss in histological subtypes
Early pregnancy loss (EPL) is a common event in human reproduction and is classified into histological subtypes such as hydropic abortion (HA) and hydatidiform moles, including complete hydatidiform moles (CHMs) and partial hydatidiform moles (PHMs). However, accurate diagnosis and improved patient ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055182 | Pride
Proteomic Hydatidiform mole Early pregnancy loss Precious diagnosis Biomarkers 
UnknownUltrasound-based incidence of coarctation of the aorta in true and false positive fetuses.
To investigate the incidence and significant ultrasound parameter changes of coarctation of the aorta (CoA) among fetuses with suspected CoA, pregnant women with suspected CoA fetuses on prenatal ultrasound examination were prospectively enrolled. The CoA presence was confirmed after birth by comput...
S-EPMC11958706 | biostudies-literature
TranscriptomicsRadiation-induced changes in gene expression in the silkworm revealed by serial analysis of gene expression
These results provide valuable information for understanding the mechanisms of radiation-induced changes in gene expression.
ORGANISM(S): Bombyx mori 
2005-06-20 | E-GEOD-2689 | biostudies-arrayexpress
UnknownGenetic predisposition of six well-defined polymorphisms in HMGB1/RAGE pathway to breast cancer in a large Han Chinese population.
Breast cancer constitutes an enormous burden in China. A strong familial clustering of breast cancer suggests a genetic component in its carcinogenesis. To examine the genetic predisposition of high mobility group box-1/receptor for advanced glycation end products (HMGB1/RAGE) pathway to breast canc...
S-EPMC5020633 | biostudies-literature
TranscriptomicsGene expression analysis between the pancreatic tissues of Pdx1-cre;Kras LSL-G12D and Pdx-cre;KrasLSL-G12D;IKK2/beta F/F mice
Constitutive Kras and NF-kB activation is identified as signature alterations in human pancreatic ductal adenocarcinoma (PDAC). Here, we report that pancreas-targeted IKK2/beta inactivation inhibited NF-kB activation and completely suppressed PDAC development. Our findings demonstrated that NF-kB is...
ORGANISM(S): Mus musculus 
2012-01-24 | E-GEOD-33322 | biostudies-arrayexpress
UnknownA promoter polymorphism in APJ gene is significantly associated with blood pressure changes and hypertension risk in Chinese women.
The aim of this study was to interrogate the gender-specific association of 5 well-defined polymorphisms in apelin/APJ system with both blood pressure changes and hypertension risk in a northeastern Chinese population. This is a population-based case-control study, including 650 hypertensive patient...
S-EPMC5349911 | biostudies-literature
ProteomicsLC-MS/MS after Immunoprecipitation with Mbd5 in zebrafish at 4dpf
To address how Mbd5 binding to m5C RNAs mediates transcriptional activation of its target genes. Using the Tg[zhsp70l:FLAGmbd5iso2-E2AGFP] zebrafish, we performed heat shock at multiple developmental stages and carried out co-immunoprecipitation (co-IP) at 4 dpf using the FLAG antibody, followed by ...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2024-06-16 | PXD048128 | Pride
Zebrafish mbd5 co-ip 
TranscriptomicsGene expression differences between the pancreatic tissues of Pdx1-Cre;KrasLSL-G12D and Pdx1-Cre;KrasLSL-G12D;IKK2/betaF/F mice
Constitutive Kras and NF-kappaB activation is identified as signature alterations in human pancreatic ductal adenocarcinoma (PDAC). However, the mechanisms of constitutive NF-kappaB activation in KrasG12D-induced PDAC are not yet understood. Here, we report that pancreas-targeted IKK2/beta inactivat...
ORGANISM(S): Mus musculus 
2012-01-24 | E-GEOD-27478 | biostudies-arrayexpress
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