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Aberrant glycosylation has been linked to many different cancer types. The blood brain barrier (BBB) is a region of the brain that regulates the entrance of ions, diseases, toxins, etc. However in breast cancer metastasis, the BBB fails to prevent the crossing of the cancer cells into the brain. Her...
ORGANISM(S): Homo sapiens (Human) 
2019-02-27 | PXD004361 | Pride
In this study, we interrogated the protein composition of exosomes purified from cell culture supernatants of 5 different RMS cell lines, by LC-MS/MS technology and analysis using bio-informatics tools. We attempted to characterize the differences and similarities between exosomes derived from ERMS ...
ORGANISM(S): Homo sapiens (Human) 
2019-08-29 | PXD007755 | Pride
Diabetic kidney disease is the major cause of end-stage kidney failure worldwide. Podocyte damage is one of the hallmarks of diabetic nephropathy, where the loss of the podocyte filtration barrier leads to proteinuria and progressive renal damage. Bradykinin (BK) is a vasoactive peptide that was sho...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-08 | PXD010015 | Pride
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