Podocyte - OmicsDI

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Unknown (1817)
Transcriptomics (1404)
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Proteomics (114)
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Organisms

Mus musculus (803)
Homo sapiens (553)
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Brucella melitensis bv. 1 str. 16M (2)
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Mycobacterium tuberculosis str. Erdman = ATCC 35801 (1)

Organisms

Mus musculus (158)
Homo sapiens (95)
Rattus norvegicus (8)
Danio rerio (2)
Mus (1)
unidentified (1)

Repository

biostudies-arrayexpress (1251)
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geo (256)
pride (87)
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jPOST (5)
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ExpressionAtlas (1)
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Tissue

Kidney (56)
Glomerular visceral epithelial cell (15)
Cell culture (11)
Epithelial cell (8)
Podocyte (sensu Diptera) (6)
Glomerular cell (4)
Renal glomerulus (4)
Blood plasma (2)
Urine (2)
Early embryonic cell (1)
Embryonic stem cell (1)
Glomerular visceral epithelium (1)
Pericardial nephrocyte (1)
Permanent cell line cell (1)
Primary cell (1)
Renal glomerular capsule (1)

Disease

Normal (6)
Membranous glomerulonephritis (6)
Nephrotic syndrome (5)
Focal segmental glomerulosclerosis (3)
Kidney disease (3)
Yersinia enterocolitica WAP infected (virulent) (1)
HIV-associated dementia (1)
Systemic lupus erythematosus (1)
Myeloid neoplasm (1)
Invasive Ductal Carcinoma (1)
No injury (1)
Mild asthma (1)
No tendon xanthomas (1)
Controled disease patient (1)
Chronic infection with geohelminth ascaris lumbricoides (1)
Murine hemochromatosis (1)
Rheumatoid arthritis (1)
Acute myelomonocytic leukaemia (1)
Leukemia (1)
Bordetella pertussis inoculated (1)
Acute Myeloid Leukemia (1)
Infected with Leishmania amazonensis (1)
Controled disease patient (1)
Lymphoma (1)
Multiple myeloma (1)
Not Available (1)
Alport syndrome (1)
Disease free (1)
Fabry disease (1)
Severe acute respiratory syndrome (1)

Technology Type

Mass Spectrometry (87)
Shotgun proteomics (56)
Bottom-up proteomics (15)
Data-independent acquisition (12)
Gel-based experiment (6)
Data-dependent acquisition (4)
Mass spectrometry (3)
Affinity purification coupled with mass spectrometry proteomics (3)
Mass spectrometry assay (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
SWATH MS (2)
Top-down proteomics (2)
All-ion fragmentation (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (22)
Illumina HiSeq 2000 (22)
Illumina HiSeq 4000 (17)
Illumina HiSeq 2500 (11)
NextSeq 500 (11)
Illumina HiSeq 1500 (9)
Illumina MiSeq (4)
Axon- GenePix4000B (3)
G2565AA DNA microarray scanner [Agilent] (2)
Generation III Array Scanner [Amersham] (2)
418 [Affymetrix] (2)
GenePix 4000B [Axon Instruments] (2)
CeMM HPC (1)
Linux (1)
TruSeq stranded Total RNA kit (Illumina) (1)
The RNeasy mini kit (Qiagen) (1)
Mac (1)
Cell culture reagents and serum (1)
KAPA mRNA HyperPrep kit (1)
Qiagen RNeasy kit (1)
Cell culture reagents and Qiagen RNEasy kit (1)
Chromium Single Cell 3’ Reagent kits v2 (1)
10X Genomics Chromium Controller (1)
Cyclone (1)
Dell T8310 (1)
Cell Sorter Aria III or Influx (BD biosciences) (1)
ArrayWoRx Multi-Format Reader [Applied Precision] (1)
Beckman Optima L-90K (1)
NanoDrop ND-2000 (Thermo Scientific),Agilent Bioanalyzer 2100 (1)
GenePix 4000B scanner (1)

Publication Date

2014 (162)
2010 (153)
2012 (145)
2015 (144)
2013 (124)
2016 (113)
2011 (108)
2008 (92)
2009 (61)
2025 (57)
2022 (53)
2024 (52)
2026 (50)
2023 (50)
2020 (45)
2021 (40)
2018 (38)
2007 (38)
2017 (36)
2019 (32)
2006 (14)
2005 (8)
2004 (4)

CHEBI ID

CHEBI:17737 (2)
CHEBI:27389 (2)
CHEBI:16113 (2)
CHEBI:33508 (2)
CHEBI:48430 (2)
CHEBI:48928 (2)
CHEBI:17050 (2)
CHEBI:18064 (2)
CHEBI:16695 (2)
CHEBI:16708 (2)
CHEBI:16668 (2)
CHEBI:16750 (2)
CHEBI:17361 (2)
CHEBI:340824 (2)
CHEBI:17924 (2)
CHEBI:17113 (2)
CHEBI:15428 (2)
CHEBI:17754 (2)
CHEBI:16958 (2)
CHEBI:16610 (2)
CHEBI:17268 (2)
CHEBI:6650 (2)
CHEBI:30746 (2)
CHEBI:17154 (2)
CHEBI:37024 (2)
CHEBI:17568 (2)
CHEBI:17750 (2)
CHEBI:15891 (2)
CHEBI:17084 (2)
CHEBI:4047 (2)

Metabolite Name

Pyridoxine (3)
Guanosine (3)
Creatine (3)
L-Phenylalanine (3)
3-Phosphoglyceric acid (2)
(R)-3-hydroxybutyrylcarnitine (2)
4-Vinylcyclohexene (2)
N-acetylarginine (2)
Gamma-glutamylglutamate (2)
Asn-Tyr (2)
Oleoyl ethanolamide (2)
4'-Methylacetophenone (2)
Palmitoleoyl Ethanolamide (2)
Lauroyl diethanolamide (2)
Eplerenone (2)
Acetylglycine (2)
Pseudouridine (2)
AMP (2)
Uracil (2)
Betaine (2)
Thymine (2)
Thiamine (2)
Lumichrome (2)
Diethanolamine (2)
CMP (2)
Carnosine (2)
5-Methoxyindoleacetate (2)
Glutathione (2)
L-Proline (2)
CDP-ethanolamine (2)

First Public Date

2026 (48)
2025 (48)
2024 (33)
2022 (31)
2014 (30)
2023 (27)
2021 (23)
2020 (20)
2019 (18)
2018 (13)
2017 (11)
2016 (4)
2015 (3)

Modification

Not available (1)

Study type

Transcription profiling by array (909)
RNA-seq of coding RNA (146)
ChIP-seq (57)
Unknown experiment type (28)
RNA-seq of coding RNA from single cells (14)
RNA-seq of non coding RNA (14)
Transcription profiling by RT-PCR (11)
Other (8)
Methylation profiling by array (6)
Methylation profiling by high throughput sequencing (6)
RNA-seq of total RNA (6)
Transcription profiling by SAGE (4)
Human - High-throughput sequencing (4)
Animal - High-throughput sequencing (4)
Proteomic profiling by array (4)
ChIP-chip by tiling array (3)
Comparative genomic hybridization by array (3)
DNA-seq (3)
High-throughput sequencing (2)
MicroRNA profiling by array (2)
Cell line - Single-cell sequencing (1)
Baseline (1)
Animal - Single-cell sequencing (1)
Human - One-color microarray (1)
Cell line - High-throughput sequencing (1)
Transcription profiling by tiling array (1)
RNAi profiling by array (1)
ChIP-chip by array (1)
Genotyping by array (1)
MicroRNA profiling by high throughput sequencing (1)

Release Date

2014 (233)
2015 (224)
2022 (218)
2016 (200)
2021 (188)
2010 (178)
2012 (175)
2023 (170)
2013 (170)
2025 (165)
2020 (158)
2018 (144)
2011 (144)
2019 (135)
2024 (130)
2017 (123)
2008 (107)
2009 (77)
2007 (42)
2026 (37)
2006 (20)
2005 (10)
2004 (8)
2003 (3)
2001 (3)
1999 (3)
2002 (1)
1997 (1)

Lab affiliation

University Hospital Cologne (13)
III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (4)
Aarhus University Department of Biomedicine DK-8000 Aarhus (3)
Department of Genome Sciences, University of Washington, Seattle (3)
Aarhus University Department of Biomedicine DK-8000 Aarhus C (2)
Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (2)
Department of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX (2)
Department of Medicine, Nephrology and Pharmacological Sciences, Icahn School of Medicine at Mount Sinai (2)
Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX (2)
Division of Nephrology, University Hospitals Namur | Place Louise Godin 15, B-5000 Namur, Belgium (2)
Dr. Jörn Dengjel Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 (2)
Proteomics Core Facility, University of Gothenburg (2)
Universitätsmedizin Greifswald Interfakultäres Institut für Genetik und Funktionelle Genomforschung Abteilung für Funktionelle Genomforschung Felix-Hausdorff-Straße 8 17487 Greifswald (2)
Aarhus University Department of Biomedicine DK-8000 Aarhus C (lab head) (1)
Bristol Renal University of Bristol UK (1)
Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany (1)
DZNE - German Center for Neurodegenerative Diseases Munich Neuroproteomics Feodor-Lynen Str. 17 D-81377 Munich Germany (1)
Department II of Internal Medicine and Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany (1)
Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne and University Hospital Cologne, Cologne, Germany (1)
Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China (1)
Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 (1)
Department of Medicine, Division of Experimental Medicine, McGill University, Montreal, QC, Canada (1)
Department of Medicine, Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. (1)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands (1)
Department of Pharmacology, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul 03722, Korea (1)
Director of the Wellcome Centre for Cell-Matrix Research Wellcome Trust Centre for Cell Matrix Research School of Biological Sciences Faculty of Biology, Medical and Health Sciences University of Manchester (1)
Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medical and Health Sciences. University of Manchester, UK. (1)
Dr. Elke Hammer Universitätsmedizin Greifswald Interfakultäres Institut für Genetik und Funktionelle Genomforschung Abteilung für Funktionelle Genomforschung Felix-Hausdorff-Straße 8 17487 Greifswald (1)
Forschugnszentrum Jülich ZEA-3 Analytics Wilhelm-Johnen-Str 52425 Jülich Germany (1)
Icahn School of Medicine at Mount Sinai Department of Pharmacological Sciences New York, NY 10029 (1)

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Impaired Glycolysis-Derived Serine Metabolism as a Key Driver of Podocyte Injury with Senescence

Chronic kidney disease (CKD) is a major health issue, with podocyte injury with senescence playing a central role in glomerulosclerosis. This study investigates the link between glycolysis-derived serine metabolism and podocyte injury with senescence, focusing on the role of phosphoglycerate kina...

2025-08-23 | MTBLS12883 | MetaboLights

Indoxyl sulfate, a uremic toxin and aryl-hydrocarbon receptor ligand, mediates progressive glomerular disease by damaging podocytes

Indoxyl sulfate (IS) is a uremic toxin and ligand of the aryl-hydrocarbon receptor (Ahr), a transcriptional regulator. Elevated serum IS may contribute to the progression of kidney disease. Therefore, we assessed mouse podocyte damage mediated by IS. Ahr was predominantly localized to the podocyte n...

ORGANISM(S): Homo sapiens

2014-10-14 | E-GEOD-51834 | biostudies-arrayexpress

Comparison of Glomerular and Podocyte mRNA Profiles in eNOS-/- Diabetic Mice Induced by Streptozotocin

We compared mRNA profiles of isolated glomeruli versus sorted podocytes between diabetic and control mice. IRG mice crossed with eNOS-/- mice were further bred with podocin-rTTA and TetON-Cre mice to permanently label podocytes before the diabetic injury. Diabetes was induced by injection of strepto...

ORGANISM(S): Mus musculus

2016-03-16 | E-GEOD-79291 | biostudies-arrayexpress

Expression data for OVE26 diabetic mouse podocyte

Podocytes form filtration barrier through foot process around glomerualar basement membrane and selectively permit permeability of molecular smaller than albumin. Diabetes can cause podocyte pathological changes leading to high urine albumin level. Diabetic mouse model OVE26 has extremly high urine...

ORGANISM(S): Mus musculus

2012-03-02 | E-GEOD-36209 | biostudies-arrayexpress

Everolimus protects podocytes via stabilizing TUBB2B and DCDC2 expression

Glomerular podocytes are highly differentiated cells that are key components of the kidney filtration units. The podocyte cytoskeleton builds the basis for the dynamic podocyte cytoarchitecture and plays a central role for proper podocyte function. Recent studies implicate that immunosuppressive age...

ORGANISM(S): Homo sapiens

2015-09-09 | E-GEOD-66107 | biostudies-arrayexpress

Genome wide mapping of H3K27me3 in differentiated mouse podocytes

We explored H3K27me3 binding sites in the genome of differentiated, conditionally immortalized mouse podocytes. Cells were allowed to differentiate for 14 days, following thermoshifting, before treatment with either vehicle (DMSO) or the S-adenosylhomocysteine hydrolase inhibitor 3-deazaneplanocin ...

ORGANISM(S): Mus musculus

2015-12-09 | E-GEOD-69610 | biostudies-arrayexpress

Effect of glomerular disease on the podocyte cell cycle

Proteomic data from three populations of sorted murine podocytes using the FUCCI (fluorescence ubiquitination cell cycle indicator) Cell Cycle Sensor: Wild-Type podocytes at G0 (WT_G0), Alport Syndrome podocytes at G0 (AS_G0), and Alport Syndrome podocytes at G1 (AS_G1). Cell populations were sorted...

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2021-01-15 | MSV000086705 | MassIVE

Gene expression in a conditionally immortalized mouse podocyte cell line

The specialized glomerular epithelial cell (podocyte) of the kidney is a complex cell that is often damaged in glomerular diseases. Study of this cell type is facilitated by an in vitro system of propagation of conditionally immortalized podocytes. Here, genes that are differentially expressed in th...

ORGANISM(S): Mus musculus

2010-08-28 | E-GEOD-23856 | biostudies-arrayexpress

Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1

Nephrotic syndrome (NS) occurs when the glomerular filtration barrier becomes excessively permeable leading to massive proteinuria. In childhood NS, dysregulation of the immune system has been implicated and increasing evidence points to the central role of podocytes in the pathogenesis. Children wi...

ORGANISM(S): Homo sapiens

2017-07-17 | E-MTAB-5235 | biostudies-arrayexpress

Podocyte Focal Adhesion Proteome

Expression proteomics analysis of focal adhesion complexes isolated from a human immortalized podocyte cell line.

ORGANISM(S): Homo sapiens (Human)

2018-12-14 | PXD010626 | Pride

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