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ProteomicsPACTS-assisted thermal proteome profiling identifies peptide-interacting proteins
The interaction between peptide ligands and protein receptors induced significant abundance changes of the target proteins, which was a signature to indicate the interaction and provide complementary information for the current thermal proteome profiling (TPP) technique
ORGANISM(S): Homo Sapiens 
2022-01-26 | PXD031246 |
ProteomicsProfiling of the proteins interacting with amyloid beta peptides in clinical samples by PACTS-TPP
Analysis and identification of Aβ1-42 peptide interaction protein in clinical samples.
ORGANISM(S): Homo Sapiens 
2024-05-23 | PXD052500 |
ProteomicsMouse ovarian Proteomic analysis after Cigarette smoke exposure
A total of 30 days of exposure to cigarette smoke (CS) or indoor air was given to 8- 23 week-old female C57BL/6 mice, then proteomics analyses were used to determine the 24 impact of CS on ovarian reserve.
ORGANISM(S): Mus Musculus 
2023-12-21 | PXD048026 |
ProteomicsKAT8-mediated PCBP1 acetylation drives neutrophil recruitment in papain-induced airway inflammation
Emerging evidence implicates KAT8 as a critical modulator of inflammatory responses in lung diseases. Bosch et al. reported that MG149, a KAT8 inhibitor, reduces pro-inflammatory gene expression in lipopolysaccharide (LPS)-stimulated murine lung slices. Additionally, Liu et al. demonstrated that KAT...
ORGANISM(S): Homo Sapiens 
2026-05-18 | PXD078474 |
ProteomicsTargeting ubiquitin-independent proteasome with small molecule increases susceptibility in pan-KRAS mutant cancers
Despite advances in the development of direct KRAS inhibitors, KRAS-mutant cancers continue to exhibit resistance to the currently available therapies. Here, we identified REGγ as a mutant KRAS-associated factor that enhances REGγ transcription through the KRAS intermediate NRF2, suggesting that the...
ORGANISM(S): Homo Sapiens 
2025-01-01 | PXD059364 |
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