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ProteomicsComprehensive Proteomic Analysis of db/db Mice by LC-MSMS
This study focuses on the comprehensive analysis of the proteome in db/db mice, a model of type 2 diabetes mellitus (T2DM), using liquid chromatography coupled with mass spectrometry (LC-MSMS). The aim is to identify and quantify proteins present in tissues and fluids of db/db mice, providing insigh...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-20 | PXD062435 | Pride
Lc-msms Db/db mice Protein quantification Protein identification Diabetes research Proteomics 
MetabolomicsDT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates

Nonalcoholic steatohepatitis (NASH) prevalence is rising with no pharmacotherapy approved. A major hurdle in NASH drug development is the poor translatability of preclinical studies to safe/effective clinical outcomes, and recent failures highlight a need to identify new targetable pathways. Dysr...

2023-04-13 | MTBLS5005 | MetaboLights
ProteomicsModulation of Microbial Bile Acid Metabolism by DT-109 Ameliorates Nonalcoholic Steatohepatitis in Nonhuman Primates
Modulation of Microbial Bile Acid Metabolism by DT-109 Ameliorates Nonalcoholic Steatohepatitis in Nonhuman Primates
ORGANISM(S): Macaca Fascicularis Fascicularis 
2023-02-10 | PXD040009 |
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