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we developed a new method for C-terminomics, in which LysargiNase and chemical derivatization were integrated to increase the identification confidence.
ORGANISM(S): Homo Sapiens 
2019-12-16 | PXD016756 |
In this study, we conducted a comprehensive multi-omics analysis, including proteomics, transcriptomics, and ubiquitinomics, to investigate the mechanism of PF-3758309 in HCT116 cells. Our results revealed that PF-3758309 promotes the degradation of RNA polymerase II subunit proteins (POLR2A/B/E) vi...
ORGANISM(S): Homo Sapiens 
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