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In this study, we used zebrafish embryos as a model system to investigate the toxic effects of MC-RR on early development and try to elucidate the underlying developmental toxicological mechanisms in a global view at posttranscriptional level. Altered expression pattern of miRNAs in embryos treated ...
ORGANISM(S): Danio rerio 
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
In this study, the hearts used for proteomics analysis were obtained from rats randomly divided into three groups (6 rats in each group): a control group (a mixture of propanediol and sodium chloride solution), a low-dose ArBu group (ArBu suspension 60 mg/kg) and a high-dose ArBu group (ArBu suspens...
ORGANISM(S): Rattus Norvegicus 
2021-09-17 | PXD028622 |
PMs-Ti⁴⁺ enables glycoproteomic analysis that integrates EVs capture and in-situ enzymatic digestion. It can directly identify intact N-glycopeptides in plasma EVs. This study reveals protein expression and glycosylation remodeling in plasma EVs from lung cancer
ORGANISM(S): Homo Sapiens 
2026-03-31 | PXD076361 |
This work used non-targeted metabolomics and screened out differential metabolites and metabolic pathways, providing a reliable theoretical basis for further study of specific markers and their specific pathways in the progression of OA.
ORGANISM(S): Homo Sapiens 
2023-04-02 | PXD041287 |
Our research team recently investigated the role of PEDV on piglet intestinal metabolism. We conducted several independent animal experiments and collected the samples for transcriptomics and proteomics. Our purpose is to identify and validate prospective targets for both diagnostic and therapeutic ...
ORGANISM(S): Sus Scrofa Sus Scrofa Domesticus 
2026-02-27 | PXD075013 |
As animals evolved from external to internal fertilization, sperm flagella, which once transiently propelled sperm in water to reach nearby eggs, developed to beat for days or even longer within the female reproductive tract. How flagella were remodeled accordingly remains unclear. Unlike externally...
ORGANISM(S): Bos Taurus 
2025-08-12 | PXD067693 |
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