To understand tumorigenesis and cancer progression of mammary epithelium, we established a cell model combining over-expression of human telomerase reverse transcriptase gene (hTERT) and heavy-ion radiation from normal human mammary epithelial cells. We subsequently used RNA-seq method to acquire th...
In the prolonged arms race between viruses and their host plants, viruses usually encode viral suppressors of RNA silencing (VSR) to overcome the hosts' defense mechanism by inhibiting RNAi. Barley stripe mosaic virus (BSMV) is an RNA virus characterized by a positive single-stranded genetic structu...
Although intensive studies have been performed to identify and characterize host factors involved in viral replication complex formation, the high dynamism of this process and the insoluble properties of the complex make it difficult to be analyzed comprehensively using traditional affinity purifica...
TurboID tags were fused to AL7 protein, and adjacent interacting proteins were enriched by biotin. The interacting proteins were identified by mass spectrometry after protein extraction, and the differences of interacting proteins before and after TMV treatment were analyzed
To investigate protein expression differences in the ischemic brain between mice treated with vehicle and MLN4924, high-throughput proteomics Liquid Chromatography-Mass Spectrometry (LC-MS)-based analysis was performed.
