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Acid and heat lability greatly hindered the study of N-phosphorylation (pArg, pHis and pLys), and limited progresses were focus on prokaryotes since the O-phosphorylation is of high abundance in eukaryotes. To meet the challenge, this paper mainly described the identification of phosphoarginine (pAr...
ORGANISM(S): Homo sapiens (Human) 
2020-07-01 | PXD009696 | Pride
Background The kidney's tubular system, composed of nephrons and collecting ducts, relies on cellular planar polarity and tight junctions to maintain structure and function. Disruptions in this polarity contribute to diseases like cystic kidney disease and cancer. Tight junctions, such as those form...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-01 | MSV000095998 | MassIVE
Autophagy is a conserved and tightly regulated intracellular quality control pathway. ULK is a key kinase in autophagy initiation, but whether ULK kinase activity also participates in late stages of autophagy remains unknown. Here, we found that the autophagosomal SNARE protein, STX17, is phosphoryl...
ORGANISM(S): Homo Sapiens 
we obtained the proteome profiling of serum and urine specimen collected from 50 COVID-19 patients and 40 healthy subjects. We then used TMT-labeled proteomics and quantified 1,494 and 3,854 proteins in serum and urine, respectively. We then explored the pathogenic characteristics in body fluids aft...
ORGANISM(S): Homo Sapiens 
2021-12-30 | PXD030662 |
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