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Proteomicsproteomic analysis of heteromorphic leaves in Populus euphratica through iTRAQ
This project employed iTRAQ to identify proteins in three types of heteromorphic leaves in Populus euphratica
ORGANISM(S): Populus Euphratica 
2020-03-01 | PXD011819 |
ProteomicsSART3 promotes homologous recombination repair by stimulating DNA–RNA hybrids removal and DNA end resection
DNA–RNA hybrids triggered by double-strand breaks (DSBs) are crucial intermediates during DSB repair, and their timely resolution requires numbers of RNA helicases, including DEAD box 1 (DDX1). However, how these helicases are recruited to DSB-induced hybrids in time remains largely unclear. Here, w...
ORGANISM(S): Homo sapiens (Human) 
2025-01-30 | PXD053595 | Pride
Sart3 Homologous recombination repair Dna–rna hybrids 
MetabolomicsExercise Activates Interferon Immune Response of the Liver via Gpld1 to Enhance Antiviral Innate Immunity

Healthy behavioral patterns could modulate organ functions to enhance the body’s immunity. However, whether exercise regulates antiviral innate immunity remains elusive. Here, we found that exercise promotes type-I IFN (IFN-I) production in the liver and enhances IFN-I immune activity of the body...

2024-04-24 | MTBLS7972 | MetaboLights
ProteomicsGlobal profiling of AMG510 modified proteins identified tumor suppressor KEAP1 as an off-target
Here, we presented a streamlined workflow to measure abundant AMG510 modified peptides including that of KRAS/G12C by direct profiling, and a pan-AMG510 antibody peptide IP workflow to profile less abundant AMG510 off-targets.
ORGANISM(S): Homo Sapiens 
2023-01-11 | PXD029449 |
ProteomicsProteomic stratification of prognosis and treatment options for small cell lung cancer
We analyzed surgically resected formalin-fixed, paraffin-embedded (FFPE) SCLC samples by proteomic profiling and stratified SCLC into three subtypes (S-I, S-II, and S-III) with distinct clinical outcomes and chemotherapy responses.
ORGANISM(S): Homo Sapiens 
PXD064316 |
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