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ProteomicsCellular protein painting for structural and binding sites analysis via lysine reactivity profiling with o-phthalaldehyde
The three-dimensional structure and the molecular interaction of proteins determine their roles in many cellular processes. Chemical protein painting with protein mass spectrometry can identify changes in structural conformations and molecular interactions of proteins including their binding sites. ...
ORGANISM(S): Homo Sapiens 
2023-10-16 | PXD046150 |
Proteomics[HPP-2.0] Integrated and high-throughput approach for sensitive analysis of tyrosine phosphoproteome
In this study, we developed a 96-well microplate-based approach to integrate all the sample preparation steps starting from cell culture to MS-compatible pTyr peptide enrichment in three consecutive 96-well microplates. By assembling engineered SH2 domain onto microplate, non-specific adsorption of ...
ORGANISM(S): Homo Sapiens 
2024-02-03 | PXD049140 |
ProteomicsStructural mass spectrometry captures residue-resolved comprehensive conformational rearrangements of a G protein-coupled receptor
GPCR structural studies with in-solution spectroscopic approaches have offered distinctive insights into GPCR activation and signaling that highly complement those yielded from structural snapshots by crystallography or cryo-EM. While most current spectroscopic approaches excel at probing structural...
ORGANISM(S): Homo Sapiens 
2024-04-26 | PXD048942 |
ProteomicsNociceptive neurons inhibit neutrophil extracellular trap formation via MLKL-licensed histone release
This data set contains the raw data of proteinomic analysis of dorsal root ganglions (DRGs) in WT and MLKL-KO mice under basal condition and after CFA treatment, and MLKL-based IP-MS analysis of WT DRGs under basal condition and after CFA treatment.
ORGANISM(S): Mus Musculus 
2026-04-16 | PXD077273 |
UnknownMortality and Morbidity in Adults With Rheumatic Heart Disease.
Not available
S-EPMC11154374 | biostudies-literature
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