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ProteomicsEnhanced limonene production in Synechococcus elongatus PCC 7942
In this study, through computational modeling and synthetic biology tools, we identified and overcame a key flux controlling node in MEP-derived terpene biosynthesis in cyanobacteria. This strategy bypasses the limitation in traditional stepwise metabolic engineering, and led to significantly higher...
ORGANISM(S): Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) 
2016-12-07 | PXD005105 | Pride
Limonene mep terpene modeling atp/nadph 
MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
MetabolomicsNon-targeted multimodal metabolomics and lipidomics data from ovine rumen fluid fractions

From an animal production and health perspective, our understanding of the metabolites in ruminant biofluids, particularly rumen fluid across different host species is poorly understood. Metabolomics is a powerful and sensitive approach for investigating low molecular weight metabolite profiles p...

2021-08-23 | MTBLS1717 | MetaboLights
UnknownDevelopment and Assessment of Screening Nomogram for Biliary Atresia Based on Hepatobiliary Ultrasonographic Features.
Not available
S-EPMC8165198 | biostudies-literature
UnknownRevealing a steroid receptor ligand as a unique PPARγ agonist.
Not available
S-EPMC3257359 | biostudies-literature
UnknownZwitterionic Electrolyte Additives Empowered Robust Zn-I2 Batteries Enduring a Low Temperature of -40 °C.
Not available
S-EPMC12850064 | biostudies-literature
UnknownExpression of exogenous human hepatic nuclear factor-1α by a lentiviral vector and its interactions with Plasmodium falciparum subtilisin-like protease 2.
Not available
S-EPMC3279685 | biostudies-literature
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
UnknownObservational and genetic evidence highlight the association of human sleep behaviors with the incidence of fracture.
Not available
S-EPMC8626439 | biostudies-literature
UnknownThe circular RNA Rap1b promotes Hoxa5 transcription by recruiting Kat7 and leading to increased Fam3a expression, which inhibits neuronal apoptosis in acute ischemic stroke.
Not available
S-EPMC10328278 | biostudies-literature
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