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UnknownNAD+-boosting agent nicotinamide mononucleotide potently improves mitochondria stress response in Alzheimer's disease via ATF4-dependent mitochondrial UPR.
Not available
S-EPMC11470026 | biostudies-literature
UnknownDepletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice.
Not available
S-EPMC8235853 | biostudies-literature
UnknownThe associations between coping resources and help-seeking intention in a sample of Chinese first-year medical students: mediation effects of coping strategies.
Not available
S-EPMC12036150 | biostudies-literature
TranscriptomicsA genome-wide transcriptome analysis reveals diverse roles of two-component system DraR-K in physiological and morphological differentiation of Streptomyces coelicolor
A novel two-component system (TCS) DraR-K was identified previously to play a differential role in antibiotic biosynthesis (ACT, RED and yCPK) of Streptomyces coelicolor M145 on defined minimal medium (MM) conditions. In order to assess whether DraR-K has more global roles, a genome-wide transcripto...
ORGANISM(S): Streptomyces coelicolor 
2014-03-10 | E-GEOD-55714 | biostudies-arrayexpress
TranscriptomicsComparative genomic and transcriptomic analysis revealed genetic characteristics related to solvent formation and xylose utilization in Clostridium acetobutylicum EA 2018
Transcriptomic profiling of gene expression in EA 2018 relative to that of ATCC824 revealed several key genes related to solvent formation. For example, spo0A and adhEII have higher expression level, and most of the acid formation related genes have lower expression level in EA 2018. Cells for RNA ...
ORGANISM(S): Clostridium acetobutylicum EA 2018 
2012-07-22 | E-GEOD-23071 | biostudies-arrayexpress
UnknownAn autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping.
Not available
S-EPMC9984425 | biostudies-literature
ProteomicsSIRT2 regulates extracellular vesicle-mediated liver-bone communication
The interplay between liver and bone metabolism remains largely uncharacterized. Here, we uncover a mechanism of liver-bone crosstalk regulated by hepatocyte SIRT2. We demonstrate that hepatocyte SIRT2 expression is increased in aged mice and elderly humans. Liver-specific SIRT2 deficiency inhibits ...
ORGANISM(S): Mus Musculus 
2023-03-27 | PXD041145 |
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