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ProteomicsLysine benzoylation - Here we report the identification and characterization of a histone mark, lysine benzoylation (Kbz). Our study identifies 22 Kbz sites on histones from HepG2 and RAW cells. This type of histone mark can be stimulated by sodium benzoate (SB), a FDA-approved drug and a widely used chemical food preservative, via generation of benzoyl CoA.
Here we report the identification and characterization of a histone mark, lysine benzoylation (Kbz). Our study identifies 22 Kbz sites on histones from HepG2 and RAW cells. This type of histone mark can be stimulated by sodium benzoate (SB), a FDA-approved drug and a widely used chemical food preser...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2018-07-11 | PXD010332 | Pride
Ptm Benzoylation Histone mark 
ProteomicsHistone Kla is regulated by cellular glycolysis
We have identified a new histone modification, which is derived from glycolysis end product, lactate. By SILAC-MS/MS based quantification, and U-13C6 glucose labeling experiments, we demonstrate that histone Kla is regulated by cellular glycolysis pathway
ORGANISM(S): Homo sapiens (Human) 
2019-08-01 | PXD014870 | Pride
Human mcf-7 cells silac 
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