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ProteomicsIntegrated proteomic and transcriptomic analyses reveal the roles of Brucella BI-1 in cell division and membrane homeostasis of Brucella suis S2
To explore the role of Brucella BI-1 in Brucella suis S2, we constructed the Brucella BI-1 deletion mutant strain and its complementary strain. We then determined the effect of Brucella BI-1 deletion on the physiological characteristics of Brucella suis S2 and revealed them via integrated transcript...
ORGANISM(S): Brucella Suis Bv. 1 Str. S2 
2020-11-13 | PXD022537 |
ProteomicsHflX mediates rifampicin resistance in Brucella by downregulating the expression of RNA polymerase-associated genes
To further investigate molecular changes associated with HflX knock during rifampicin exposure, we performed label-free quantitative proteomic analysis. The WT and ΔhflX strains were cultured for three generations in the presence of 1/2 MIC rifampicin (1 μg/mL) and harvested during the logarithmic g...
ORGANISM(S): Brucella Abortus 2308 
2026-03-19 | PXD075846 |
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