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ProteomicsSoluble epoxide hydrolase in the liver orchestrates abdominal aortic aneurysm formation
The liver plays an important role in cardiovascular disease by amplifying systemic inflammation, while the underlying mechanisms remain to be defined. Soluble epoxide hydrolase (sEH) is a pro-inflammatory enzyme and pharmacological inhibition of sEH was shown to protect against various inflammatory ...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-07 | PXD073197 | Pride
Angiotensin ii Calcium chloride Liver Soluble epoxide hydrolase Abdominal aortic aneurysm 
ProteomicsInhibition of AhR improves cortical bone and skeletal muscle function via preservation of neuromuscular junctions
This project aimed to assess the role of pharmacological inhibition of the aryl hydrocarbon receptor (AhR) on skeletal muscle and cortical bone health in aged mice. As part of a broader systems biology approach, proteomic profiling was employed to investigate molecular mediators of neuromuscular jun...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-06 | PXD065529 | Pride
Lc-msms  aryl hydrocarbon receptor  proteomics 
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