B12 is a compound that has neuroprotective effects. We investigated the protein expression profile associated with the neuroprotective effects of B12 on human neuronal cells SH-SY5Y using label-free quantitative proteomics.
A DIA workflow, which is constructed on a quadrupole-Orbitrap LC-MS platform, is used to reveal perturbed proteins between ccRCC and para-carcinoma tissues.
Hepatitis B virus (HBV) infection is a major health problem worldwide. Recent evidence suggests that various viruses can manipulate the infection process by secretion of specific viral and cellular components into exosomes, small nanometer-sized (30-150 nm) vesicles secreted from various cells. Howe...
tumor necrosis factor-related apoptosis-inducing liagand is one of the promising cancer therapeutic, however, many tumors have developed different degrees of drug resistance during TRAIL treatment. the mechanism by which is unvlear, and here we reasoned that systematic proteomic and phosphoproteomic...
Thirteen paired pre- and post-nCRT sera from rectal cancer patients were analyzed by isobaric tags for relative and absolute quantitation (iTRAQ) method. Twenty-five proteins were selected for validation by parallel reaction monitoring (PRM) in ninety-one patients.
