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TMT-based quantitative proteomics was performed on lung tissues derived from SD rats which were treated with monocrotaline (MCT) for 1to 4 weeks. Similar analysis was performed with RV tissues from rats treated with MCT for 3 weeks. In addition, phosphoproteomic analysis was performed with lung and ...
ORGANISM(S): Rattus Norvegicus 
2022-11-25 | PXD038462 |
The amygdala plays a key role in the pathophysiology of depression, but the molecular mechanisms underlying amygdalar hyperactivity in depression remain unclear. In this study, we used a chronic mild stress (CMS) protocol to separate susceptible and insusceptible rat subgroups. Proteomes in the amyg...
ORGANISM(S): Rattus Norvegicus 
2019-01-15 | PXD044124 |
We conducted unbiased mass spectrometric experiments to evaluate the specificity of dFUS-E9C. In these studies, Neuro-2a cells were treated with dFUS-E9C. The result revealed the detection of more than 5000 proteins, among which there was a notable degradation of FUS, confirming the targeted action ...
ORGANISM(S): Mus Musculus 
2025-04-04 | PXD062671 |
We conducted unbiased mass spectrometric experiments to evaluate the specificity of siFUS. In these studies, Neuro-2a cells were treated with siFUS. The result revealed the detection of more than 5000 proteins, among which there was a notable degradation of FUS, confirming the targeted action of siF...
ORGANISM(S): Mus Musculus 
2025-04-07 | PXD062670 |
we report a Target Responsive Accessibility Profiling (TRAP) approach for the global and quantitative analysis of glycolytic metabolites targetome in native cancer cell milieu.
ORGANISM(S): Homo Sapiens 
2020-11-17 | PXD022568 |
Dietary interventions are effective ways to extend or shorten lifespan. By examining midlife hepatic gene expressions in mice under different dietary conditions, which resulted in different lifespans and aging-related phenotypes, we were able to identify genes and pathways that modulate the aging pr...
ORGANISM(S): Mus musculus 
Dietary interventions are effective ways to extend or shorten lifespan. By examining midlife hepatic gene expressions in mice under different dietary conditions, which resulted in different lifespans and aging-related phenotypes, we were able to identify genes and pathways that modulate the aging pr...
ORGANISM(S): Mus musculus 
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