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ProteomicsDevelopment of LC-FAIMS-MS and its application to lipidomics study of Acinetobacter baumannii infection
Here we present the development and application of LC-FAIMS-MS/MS based platform for untargeted lipidomics. The combination of normal phase liquid chromatography (NPLC), which can separate different types of phospholipids based on their head groups, and high-resolution MS (HRMS) offers a powerful qu...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD055224 | Pride
Faims Lc-ms Acinetobacter baumannii Serum Lipidomics 
TranscriptomicsThe pattern of gene expression in human CD34(+) stem/progenitor cells
We have analyzed the pattern of gene expression in human primary CD34(+) stem/progenitor cells. We identified 42,399 unique serial analysis of gene expression (SAGE) tags among 106,021 SAGE tags collected from 2.5 x 10(6) CD34(+) cells purified from bone marrow. Of these unique SAGE tags, 21,546 mat...
ORGANISM(S): Homo sapiens 
2005-02-28 | E-GEOD-2346 | biostudies-arrayexpress
TranscriptomicsThe pattern of gene expression in human CD15+ myeloid progenitor cells
We performed a genome-wide analysis of gene expression in primary human CD151 myeloid progenitor cells. By using the serial analysis of gene expression (SAGE) technique, we obtained quantitative information for the expression of 37,519 unique SAGE-tag sequences. Of these unique tags, (i) 25% were de...
ORGANISM(S): Homo sapiens 
2008-10-03 | E-GEOD-13007 | biostudies-arrayexpress
MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
TranscriptomicsGene Expression Profiles with Common Translocations in Acute Myeloid Leukemia (AML) using SAGE
SAGE was used to profile gene expression in leukemic myeloid progenitor cells of AML patients with t(8;21), t(15;17), t(9;11) and inv(16). Keywords: SAGE analysis of gene expression in leukemic myeloid progenitor cells isolated from bone marrow Bone marrow cells from 4 patients with de novo t(9;11),...
ORGANISM(S): Homo sapiens 
2005-11-30 | E-GEOD-3255 | biostudies-arrayexpress
Proteomicsreprogramming enables the auxiliary diagnosis of breast cancer by automated breast volume scanner
Our study identified metabolic features both in benign and malignant breast tumors and in invasive and non-invasive breast cancer. Combined ultrasound ABVS and a panel of differential serum metabolites could further improve the accuracy of preoperative diagnosis of breast cancer and guide surgical t...
ORGANISM(S): Homo Sapiens 
2022-09-14 | PXD036696 |
ProteomicsLC-MS/MS proteomic analysis of candidate BATF2-binding proteins
Label-free Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS) proteomic analysis of candidate BATF2-binding proteins
ORGANISM(S): Homo Sapiens 
2022-10-27 | PXD037788 |
ProteomicsTo explore potential proteins that bind to usp16
HEK293T cells were transfected with FLag-USP16, and cells were performed with co-immunoprecipitation by Flag antibody or IgG with protein A/G beads.
ORGANISM(S): Homo Sapiens 
2023-09-01 | PXD045021 |
ProteomicsCopper exposure aggravates motor phenotype via inhibiting mitophagy in SOD1G93A transgenic mice
Background Amyotrophic lateral sclerosis (ALS) is an age-dependent and incurable neurodegenerative disease. It is pathologically characterized by selective degeneration of motor neurons resulting in a catastrophic loss of motor function. Previous studies showed that excess copper (Cu) might have a r...
ORGANISM(S): Mus Musculus 
2023-01-29 | PXD039728 |
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