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TranscriptomicsMechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch
Hypoxia-induced cell injury has been related to multiple pathological conditions. In order to render hypoxia-sensitive cells and tissues resistant to low O2 environment, in this current study, we used Drosophila melanogaster as a model to dissect the mechanisms underlying hypoxia-tolerance. A D. mel...
ORGANISM(S): Drosophila melanogaster 
2010-06-25 | E-GEOD-8803 | biostudies-arrayexpress
TranscriptomicsMicroarray skeletal muscle miR-499 overexpressing mice
This experiment was conducted to identify target genes of the microRNA-499 in skeletal muscle of transgenic mice that overexpressed miR-499. The following abstract from the submitted manuscript describes the major findings of this work. Coupling of mitochondrial function and skeletal muscle f...
ORGANISM(S): Mus musculus 
2016-09-03 | E-GEOD-72581 | biostudies-arrayexpress
TranscriptomicsAlterations in the gene expression profile in SKOV3 cells exposed to elaiophylin
Elaiophylin was screened and identified as a novel autophagy inhibitor, with significant antitumor efficacy as a single agent. To explore the mechanisms by which elaiophylin kills cancer cells, NimbleGen 12x135K microarrays were used to find the gene expression changes in SKOV3 cells treated with el...
ORGANISM(S): Homo sapiens 
2022-06-07 | GSE205529 | GEO
UnknownEffect of non-pharmaceutical interventions for containing the COVID-19 outbreak in China.
Not available
S-EPMC7276028 | biostudies-literature
ProteomicsA proteomic landscape of diffuse-type gastric cancer
Here we present a dataset from 84 DGC patients with paired tumor and nearby tissue. Tumors and their nearby tissues were evaluated by pathologists. Nearby tissues were designated as non-cancerous and were greater than 5 cm away from the surgery margin. Hematoxylin and eosin (H&E) stained sections we...
ORGANISM(S): Homo sapiens (Human) 
2018-02-09 | PXD008840 | Pride
Gastric cancer Proteome 
TranscriptomicsTranscriptomic profiles of Japanese medaka (Oryzias latipes) in response to alkalinity stress
Alkalinity stress is considered to be one of the major stressors for fish in saline-alkali water. Thus, it is of great significance from both aquaculture and physiological viewpoint to understand the molecular genetic response of aquatic organisms to alkalinity stress. The objective of this study is...
ORGANISM(S): Oryzias latipes 
2014-01-24 | E-GEOD-27298 | biostudies-arrayexpress
MetabolomicsEffects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice

With the rapid development of 5G networks, the influence of the radiofrequency field (RF) generated from 5G communication equipment on human health are gathering increasing attention. This study aimed at assessing the effects of long-term exposure to 4.9 GHz (one of the working frequency of 5G co...

2022-11-08 | MTBLS4186 | MetaboLights
UnknownL-methionine promotes CD8<sup>+</sup> T cells killing hepatocellular carcinoma by inhibiting NR1I2/PCSK9 signaling.
Not available
S-EPMC11997342 | biostudies-literature
UnknownTree age did not affect the leaf anatomical structure or ultrastructure of Platycladus orientalis L. (Cupressaceae).
Not available
S-EPMC6824329 | biostudies-literature
ProteomicsHuman follicular fluid neurotransmitters LC-MSMS
Pretreated human follicular fluid was prepared for targeted metabolomics experiments. For this purpose, 12-point standard calibration curves in the respective range with reference material were measured, and the limit of detection (LOD) and limit of quantification (LOQ) for each neurotransmitter und...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD031560 | Pride
Human Lc-msms Follicular fluid 
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