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MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
UnknownDe novo biosynthesis of rubusoside and rebaudiosides in engineered yeasts.
Not available
S-EPMC9160076 | biostudies-literature
UnknownPTEN-L inhibits mitophagy and GSDME-dependent pyroptosis via Parkin dephosphorylation
Not available
S-SCDT-10_1038-S44319-026-00957-4 | biostudies-other
ModelsZou2012 - Genome-scale metabolic network of Ketogulonicigenium vulgare (iWZ663)
Zou2012 - Genome-scale metabolic network of Ketogulonicigenium vulgare (iWZ663) This model is described in the article: Genome-scale metabolic model of Helicobacter pylori 26695. Schilling CH, Covert MW, Famili I, Church GM, Edwards JS, Palsson BO. J. Bacteriol. 2002 Aug; 184(...
2015-07-30 | MODEL1507180039 | BioModels
UnknownPSTK exerts protective role in cisplatin-tubular cell injury via BAX/BCL2/Caspase3 pathway.
Not available
S-EPMC11723822 | biostudies-literature
ProteomicsIn situ Analysis of Nanoparticle Soft Corona and Dynamic Evolution
How soft corona i.e., the protein corona’s outer layer contributes to “biological” identity of nanomaterials (NMs) is largely unknown due to a longstanding challenge in capturing protein composition of the soft corona in situ. We herein develop an in situ “Fishing” method that can monitor the dynami...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD033976 | Pride
Protein corona Mouse serum 
ProteomicsIntegrated proteome and phosphoproteome analysis of interscapular brown adipose and subcutaneous white adipose tissues upon high fat diet feeding in mouse
Thermogenesis is a promising approach to limit weight gain in response to excess nutrition. In contrast to cold-induced thermogenesis, the molecular and cellular mechanisms of diet-induced thermogenesis (DIT) have not been fully characterized. Here, we explored the response of brown adipose tissue (...
ORGANISM(S): Mus Musculus 
2022-04-01 | PXD032888 |
TranscriptomicsDirect conversion of fibroblasts to neurons by a new mechanism – p53 regulation
Direct conversion from fibroblast to neuron has recently been successfully induced bypassing the pluripotent state. However, the conversion takes a few months with low percentages of success. Here we found that depletion of p53, which can converted fibroblasts into three major neural lineages: neuro...
ORGANISM(S): Homo sapiens 
2013-04-26 | E-GEOD-46392 | biostudies-arrayexpress
TranscriptomicsLinking immortalization to direct conversion of human fibroblasts to neurons
Direct conversion from fibroblasts to neurons is a potential cell replacement therapy for neurological disorders, and a variety of combinations of transcription factors have been tried. We notice that the efficiency of conversion from aging fibroblasts was much lower than in early stage cells, which...
ORGANISM(S): Homo sapiens 
2012-12-28 | E-GEOD-43175 | biostudies-arrayexpress
ProteomicsIntegration of Urine Proteomic and Metabolomic profiling Reveals Novel Insights into Neuroimmune Dysfunction in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a complex set of neurodevelopmental diseases. However, the etiology and pathogenesis of ASD is largely unknown. An integrated proteomics and metabolomics approach was performed on urine sampled from diagnosed ASD children and typical children. All urine protein samp...
ORGANISM(S): Homo Sapiens 
2022-02-11 | PXD031652 |
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