Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: Hu Zhou
PROVIDER: PXD032888 | iProX | Fri Apr 01 00:00:00 BST 2022
REPOSITORIES: iProX
Wang Yuqiu Y Li Junmin J Lu Dayun D Meng Qian Q Song Nixue N Zhou Hu H Xiao Xiao X Sun Liming L Zhu Hongwen H
Journal of proteomics 20220129
Thermogenesis is a promising approach to limit weight gain in response to excess nutrition. In contrast to cold-induced thermogenesis, the molecular and cellular mechanisms of diet-induced thermogenesis (DIT) have not been fully characterized. Here, we explored the response of brown adipose tissue (BAT) and subcutaneous white adipose tissue (sWAT) to high fat diet (HFD) using proteome and phosphoproteome analysis. We observed that after HFD, Uncoupling protein 1 (UCP1) and its phosphorylation we ...[more]