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MetabolomicsApoplastic metabolomics reveals sugars as mesophyll messengers regulating guard cell ion transport under red light
Here we sought to identify mesophyll messenger(s) that promote stomatal opening under red light. We first established a method to isolate leaf apoplastic fluids from Arabidopsis thaliana and Vicia faba and ascertained that the apoplastic fluid enhances red light-induced stomatal opening. We then app...
2025-06-23 | MTBLS5383 | MetaboLights
MetabolomicsGNPS - Serum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | GNPS
MetabolomicsComprehensive transcriptome and metabolome analysis revealed the primary molecular regulatory pathways of skin development in Yulin black duck during embryonic stage
Skin color is one of the key characteristics the duck possesses which is used to determine the market value because it affects the consumer's purchasing decisions. People tend to prefer ducks with black skin because they are more suitable for making soup. This study was conducted to identify the sig...
2026-08-24 | MTBLS14916 | MetaboLights
ProteomicsSerum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | MassIVE
ProteomicsProteomic analysis of extracellular vesicles from inflammatory fibroblasts in colorectal cancer lung metastasis
Pulmonary metastasis is a major cause of mortality in colorectal cancer (CRC), and the tumor microenvironment plays a critical role in metastatic progression. In particular, inflammatory fibroblasts have been implicated in shaping the metastatic niche; however, the molecular characteristics of their...
ORGANISM(S): Homo Sapiens 
2026-03-20 | PXD075933 |
ProteomicsCeramide Disrupts TM9SF2-PGK1 Axis to Redirect PD-L1 Trafficking and Enhance Antitumor Immunity
The programmed cell death protein 1 (PD-1) / programmed death-ligand 1 (PD-L1) axis represents a cornerstone of cancer immunotherapy, yet the dynamic shuttling of PD-L1 between endosomal recycling and lysosomal degradation routes limits durable responses. Using a CRISPR screen targeting glycosphingo...
ORGANISM(S): Homo Sapiens 
2026-02-27 | PXD075012 |
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