Sort   by:  
 Page size 
Aberrant sterol lipid metabolism is associated with physiological dysfunctions in the aging brain and aging-dependent disorders such as neurodegenerative diseases. There is an unmet demand to comprehensively profile sterol lipids spatially and temporally in different brain regions during aging. Here...
2021-05-24 | MTBLS2457 | MetaboLights

In this study, lipid alterations in Beagle dog’s liver caused by Toxocara canis infection were investigated by using liquid chromatography with tandem mass spectrometry at 12 hours post infection (hpi), 24 hpi and 36 days post infection (dpi). A total of 6 categories and 42 subclasses of...

2022-08-30 | MTBLS4015 | MetaboLights
To identify human DTX2 proximal proteome, the BioID-DTX2 fusion protein was expressed in DTX2 KO HeLa cells. The biotinylated proteins were pulled down and subjected to mass spectrometry analysis.
ORGANISM(S): Homo Sapiens 
2022-10-11 | PXD023795 |
Rheb is a small G protein that functions as the direct activator of the mechanistic target of rapamycin complex 1 (mTORC1) to coordinate signaling cascades in response to nutrients and growth factors. Despite extensive studies, the guanine nucleotide exchange factor (GEF) that directly activates Rhe...
ORGANISM(S): Homo Sapiens 
2022-09-29 | PXD037078 |
Characterization of proteome changes to zebrafish and fathead minnow following exposure to the Anatoxin-a surrogate anatoxin-fumerate.
ORGANISM(S): Pimephales Promelas (ncbitaxon:90988) Danio Rerio (ncbitaxon:7955) 
2023-11-29 | MSV000093536 | MassIVE
Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma, exhibits marked clinical heterogeneity driven by poorly understood molecular mechanisms. Identifying the molecular characteristics of different RMS subtypes and the molecular pathways influencing RMS treatment response and recurr...
ORGANISM(S): Homo Sapiens 
2025-10-14 | PXD069421 |
Telomere homeostasis, crucial for various biological processes, relies on telomerase activity. We identified ZC3H15 as a novel telomerase-interacting protein. Its deletion unexpectedly increased telomerase activity but led to shortened telomeres and cellular senescence. ZC3H15 interacts with telomer...
ORGANISM(S): Homo Sapiens 
2024-05-06 | PXD052036 |
Interferon regulatory factor 2 binding protein 2 (Irf2bp2) is a corepressor of Irf2 that suppresses inflammatory gene expression and promotes the M2 macrophage phenotype in bone marrow derived macrophages (BMDM). Loss of Irf2bp2 in male macrophages promotes an inflammatory phenotype. Here, we compar...
ORGANISM(S): Mus musculus domesticus 
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common monogenic genetic disorders, caused by mutations in receptor PKD1 or ion channel PKD2, and is characterized by progressive renal cyst development with additional hepatic and extrarenal manifestations. As effective treatme...
ORGANISM(S): Homo Sapiens 
2026-02-13 | PXD074819 |
Sort   by:  
 Page size